[Hub]/) : Traits : Arm fat mass (left) : ← →

chr7:1,606,847-3,581,391

Best TWAS P=2.62e-15 · Best GWAS P=9.41e-14 conditioned to 0.0366

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
11	ROSMAP	Brain Pre-frontal Cortex	AMZ1	0.09	0.05	lasso	6	0.04	2.4e-06	-7.1	7.9	2.6e-15	-0.90	0.04	0.96	TRUE
16	The Cancer Genome Atlas	Prostate Adenocarcinoma	MAD1L1	0.09	0.01	blup	206	0.04	1.1e-04	4.4	-5.3	1.1e-07	-0.10	0.09	0.43	TRUE
3	GTEx	Cells EBV-transformed lymphocytes	GNA12	0.46	0.51	lasso	5	0.50	7.9e-19	-7.4	-7.3	2.1e-13	0.99	0.00	1.00	FALSE
9	GTEx	Whole Blood	GNA12	0.09	0.01	enet	4	0.00	3.3e-01	-7.1	-7.3	3.6e-13	0.94	0.02	0.92	FALSE
13	The Cancer Genome Atlas	Esophageal Carcinoma	AMZ1	0.18	0.05	blup	69	0.05	1.4e-02	4.9	-7.1	1.5e-12	0.71	0.01	0.71	FALSE
8	GTEx	Esophagus Muscularis	GNA12	0.32	0.31	lasso	3	0.34	2.1e-21	-7.1	-6.9	5.5e-12	0.94	0.02	0.98	FALSE
1	CommonMind	Brain Pre-frontal Cortex	AMZ1	0.19	0.12	enet	22	0.13	5.7e-16	5.0	6.3	3.7e-10	-0.43	1.00	0.00	FALSE
12	YFS	Blood	GNA12	0.23	0.15	bslmm	570	0.25	4.5e-82	5.4	-5.9	3.2e-09	0.52	1.00	0.00	FALSE
10	NTR	Blood	GNA12	0.07	0.03	bslmm	597	0.06	1.3e-17	-4.7	-5.7	1.4e-08	0.63	0.92	0.08	FALSE
15	The Cancer Genome Atlas	Lung Adenocarcinoma	GNA12	0.03	0.01	enet	7	0.02	1.5e-03	1.9	-5.5	3.8e-08	0.78	0.05	0.77	FALSE
7	GTEx	Esophagus Mucosa	GNA12	0.16	0.13	lasso	3	0.13	3.0e-09	-6.4	-5.5	3.9e-08	0.87	0.06	0.94	FALSE
6	GTEx	Esophagus Gastroesophageal Junction	GNA12	0.20	0.12	lasso	6	0.12	3.4e-05	-3.2	-5.5	4.4e-08	0.86	0.04	0.95	FALSE
14	The Cancer Genome Atlas	Brain Lower Grade Glioma	AMZ1	0.04	0.04	lasso	3	0.02	1.3e-03	4.9	5.4	5.2e-08	-0.60	0.04	0.90	FALSE
2	GTEx	Artery Tibial	GNA12	0.24	0.13	enet	20	0.22	3.5e-17	-7.1	-5.4	6.4e-08	0.84	0.03	0.97	FALSE
5	GTEx	Colon Sigmoid	GNA12	0.14	0.05	lasso	3	0.03	3.6e-02	-3.0	-5.2	1.5e-07	0.87	0.03	0.89	FALSE
4	GTEx	Cells Transformed fibroblasts	GNA12	0.21	0.11	lasso	11	0.15	1.7e-11	-7.1	-5.2	2.5e-07	0.86	0.03	0.97	FALSE