[Hub]/) : Traits : Arm fat mass (left) :

chr7:1,606,847-3,581,391

Best TWAS P=2.62e-15 · Best GWAS P=9.41e-14 conditioned to 0.0366

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex AMZ1 0.19 0.12 enet 22 0.13 5.7e-16 5.0 6.3 3.7e-10 -0.43 1.00 0.00 FALSE
2 GTEx Artery Tibial GNA12 0.24 0.13 enet 20 0.22 3.5e-17 -7.1 -5.4 6.4e-08 0.84 0.03 0.97 FALSE
3 GTEx Cells EBV-transformed lymphocytes GNA12 0.46 0.51 lasso 5 0.50 7.9e-19 -7.4 -7.3 2.1e-13 0.99 0.00 1.00 FALSE
4 GTEx Cells Transformed fibroblasts GNA12 0.21 0.11 lasso 11 0.15 1.7e-11 -7.1 -5.2 2.5e-07 0.86 0.03 0.97 FALSE
5 GTEx Colon Sigmoid GNA12 0.14 0.05 lasso 3 0.03 3.6e-02 -3.0 -5.2 1.5e-07 0.87 0.03 0.89 FALSE
6 GTEx Esophagus Gastroesophageal Junction GNA12 0.20 0.12 lasso 6 0.12 3.4e-05 -3.2 -5.5 4.4e-08 0.86 0.04 0.95 FALSE
7 GTEx Esophagus Mucosa GNA12 0.16 0.13 lasso 3 0.13 3.0e-09 -6.4 -5.5 3.9e-08 0.87 0.06 0.94 FALSE
8 GTEx Esophagus Muscularis GNA12 0.32 0.31 lasso 3 0.34 2.1e-21 -7.1 -6.9 5.5e-12 0.94 0.02 0.98 FALSE
9 GTEx Whole Blood GNA12 0.09 0.01 enet 4 0.00 3.3e-01 -7.1 -7.3 3.6e-13 0.94 0.02 0.92 FALSE
10 NTR Blood GNA12 0.07 0.03 bslmm 597 0.06 1.3e-17 -4.7 -5.7 1.4e-08 0.63 0.92 0.08 FALSE
11 ROSMAP Brain Pre-frontal Cortex AMZ1 0.09 0.05 lasso 6 0.04 2.4e-06 -7.1 7.9 2.6e-15 -0.90 0.04 0.96 TRUE
12 YFS Blood GNA12 0.23 0.15 bslmm 570 0.25 4.5e-82 5.4 -5.9 3.2e-09 0.52 1.00 0.00 FALSE
13 The Cancer Genome Atlas Esophageal Carcinoma AMZ1 0.18 0.05 blup 69 0.05 1.4e-02 4.9 -7.1 1.5e-12 0.71 0.01 0.71 FALSE
14 The Cancer Genome Atlas Brain Lower Grade Glioma AMZ1 0.04 0.04 lasso 3 0.02 1.3e-03 4.9 5.4 5.2e-08 -0.60 0.04 0.90 FALSE
15 The Cancer Genome Atlas Lung Adenocarcinoma GNA12 0.03 0.01 enet 7 0.02 1.5e-03 1.9 -5.5 3.8e-08 0.78 0.05 0.77 FALSE
16 The Cancer Genome Atlas Prostate Adenocarcinoma MAD1L1 0.09 0.01 blup 206 0.04 1.1e-04 4.4 -5.3 1.1e-07 -0.10 0.09 0.43 TRUE