[Hub]/) : Traits : Arm fat-free mass (left) :

chr1:752,566-3,191,909

Best TWAS P=7.84e-12 · Best GWAS P=3.56e-10 conditioned to 0.00241

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SLC35E2 0.35 0.15 enet 24 0.17 1.0e-20 -6.0 5.4 6.1e-08 0.32 0.02 0.98 FALSE
2 GTEx Adipose Subcutaneous C1orf86 0.15 0.05 enet 10 0.04 2.0e-04 -4.6 -6.2 6.0e-10 -0.11 0.38 0.14 FALSE
3 GTEx Adipose Visceral Omentum RP1-283E3.4 0.26 0.05 enet 25 0.16 1.5e-08 -3.0 -5.7 9.8e-09 -0.27 0.14 0.15 TRUE
4 GTEx Brain Cerebellar Hemisphere NADK 0.18 0.11 lasso 7 0.09 3.1e-03 -5.7 -5.8 5.8e-09 -0.27 0.03 0.64 FALSE
5 GTEx Brain Cerebellar Hemisphere RP5-890O3.9 0.24 0.02 lasso 9 0.02 1.3e-01 -6.2 6.8 7.8e-12 0.28 0.02 0.66 TRUE
6 GTEx Esophagus Gastroesophageal Junction RP11-181G12.2 0.16 0.02 enet 18 0.01 1.1e-01 4.9 5.2 1.7e-07 0.01 0.11 0.07 TRUE
7 GTEx Esophagus Mucosa TMEM52 0.17 0.18 lasso 2 0.20 2.9e-13 -5.6 5.6 2.8e-08 0.24 0.28 0.72 FALSE
8 GTEx Esophagus Muscularis RP11-181G12.2 0.23 0.14 lasso 4 0.19 1.0e-11 4.3 5.2 2.0e-07 0.00 0.97 0.03 FALSE
9 GTEx Lung NADK 0.07 0.03 lasso 3 0.02 8.5e-03 5.3 -5.9 4.5e-09 -0.27 0.03 0.90 FALSE
10 GTEx Muscle Skeletal NADK 0.06 0.00 enet 9 0.00 1.3e-01 -5.7 -6.0 1.5e-09 -0.23 0.05 0.83 FALSE
11 GTEx Muscle Skeletal TMEM52 0.11 0.08 lasso 6 0.10 7.2e-10 -5.8 5.8 5.1e-09 0.26 0.13 0.87 FALSE
12 GTEx Skin Not Sun Exposed Suprapubic TMEM52 0.19 0.18 lasso 4 0.14 2.6e-08 5.3 5.7 1.4e-08 0.25 0.04 0.96 FALSE
13 GTEx Skin Sun Exposed Lower leg TMEM52 0.17 0.14 lasso 7 0.15 2.0e-12 5.9 6.0 2.6e-09 0.26 0.04 0.96 FALSE
14 GTEx Spleen TMEM52 0.47 0.21 lasso 5 0.22 2.3e-06 -3.6 -5.2 2.2e-07 -0.15 0.26 0.32 FALSE
15 METSIM Adipose TNFRSF14 0.07 0.05 blup 373 0.05 1.9e-07 3.8 6.4 1.9e-10 -0.01 0.91 0.05 TRUE
16 ROSMAP Brain Pre-frontal Cortex C1orf222 0.11 0.14 enet 18 0.14 1.8e-17 -4.2 5.8 5.9e-09 0.22 0.98 0.02 FALSE
17 ROSMAP Brain Pre-frontal Cortex MMP23B 0.05 0.04 lasso 2 0.03 1.9e-04 -5.4 -5.4 8.1e-08 -0.24 0.08 0.90 FALSE
18 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma TMEM52 0.02 0.01 blup 37 0.02 6.6e-03 -5.6 5.9 4.1e-09 0.26 0.01 0.77 FALSE