[Hub]/) : Traits : Arm fat-free mass (left) : →

chr1:752,566-3,191,909

Best TWAS P=7.84e-12 · Best GWAS P=3.56e-10 conditioned to 0.00241

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
5	GTEx	Brain Cerebellar Hemisphere	RP5-890O3.9	0.24	0.02	lasso	9	0.02	1.3e-01	-6.2	6.8	7.8e-12	0.28	0.02	0.66	TRUE
15	METSIM	Adipose	TNFRSF14	0.07	0.05	blup	373	0.05	1.9e-07	3.8	6.4	1.9e-10	-0.01	0.91	0.05	TRUE
3	GTEx	Adipose Visceral Omentum	RP1-283E3.4	0.26	0.05	enet	25	0.16	1.5e-08	-3.0	-5.7	9.8e-09	-0.27	0.14	0.15	TRUE
6	GTEx	Esophagus Gastroesophageal Junction	RP11-181G12.2	0.16	0.02	enet	18	0.01	1.1e-01	4.9	5.2	1.7e-07	0.01	0.11	0.07	TRUE
2	GTEx	Adipose Subcutaneous	C1orf86	0.15	0.05	enet	10	0.04	2.0e-04	-4.6	-6.2	6.0e-10	-0.11	0.38	0.14	FALSE
10	GTEx	Muscle Skeletal	NADK	0.06	0.00	enet	9	0.00	1.3e-01	-5.7	-6.0	1.5e-09	-0.23	0.05	0.83	FALSE
13	GTEx	Skin Sun Exposed Lower leg	TMEM52	0.17	0.14	lasso	7	0.15	2.0e-12	5.9	6.0	2.6e-09	0.26	0.04	0.96	FALSE
18	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	TMEM52	0.02	0.01	blup	37	0.02	6.6e-03	-5.6	5.9	4.1e-09	0.26	0.01	0.77	FALSE
9	GTEx	Lung	NADK	0.07	0.03	lasso	3	0.02	8.5e-03	5.3	-5.9	4.5e-09	-0.27	0.03	0.90	FALSE
11	GTEx	Muscle Skeletal	TMEM52	0.11	0.08	lasso	6	0.10	7.2e-10	-5.8	5.8	5.1e-09	0.26	0.13	0.87	FALSE
4	GTEx	Brain Cerebellar Hemisphere	NADK	0.18	0.11	lasso	7	0.09	3.1e-03	-5.7	-5.8	5.8e-09	-0.27	0.03	0.64	FALSE
16	ROSMAP	Brain Pre-frontal Cortex	C1orf222	0.11	0.14	enet	18	0.14	1.8e-17	-4.2	5.8	5.9e-09	0.22	0.98	0.02	FALSE
12	GTEx	Skin Not Sun Exposed Suprapubic	TMEM52	0.19	0.18	lasso	4	0.14	2.6e-08	5.3	5.7	1.4e-08	0.25	0.04	0.96	FALSE
7	GTEx	Esophagus Mucosa	TMEM52	0.17	0.18	lasso	2	0.20	2.9e-13	-5.6	5.6	2.8e-08	0.24	0.28	0.72	FALSE
1	CommonMind	Brain Pre-frontal Cortex	SLC35E2	0.35	0.15	enet	24	0.17	1.0e-20	-6.0	5.4	6.1e-08	0.32	0.02	0.98	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	MMP23B	0.05	0.04	lasso	2	0.03	1.9e-04	-5.4	-5.4	8.1e-08	-0.24	0.08	0.90	FALSE
8	GTEx	Esophagus Muscularis	RP11-181G12.2	0.23	0.14	lasso	4	0.19	1.0e-11	4.3	5.2	2.0e-07	0.00	0.97	0.03	FALSE
14	GTEx	Spleen	TMEM52	0.47	0.21	lasso	5	0.22	2.3e-06	-3.6	-5.2	2.2e-07	-0.15	0.26	0.32	FALSE