[Hub]/) : Traits : Arm fat-free mass (left) :

chr1:40,748,755-42,542,658

Best TWAS P=1.21e-35 · Best GWAS P=9.05e-28 conditioned to 0.0164

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta CTPS1 0.10 0.00 enet 8 0.00 4.6e-01 8.399 8.8 1.3e-18 0.75 0.05 0.57 FALSE
2 GTEx Artery Coronary CTPS1 0.25 -0.01 enet 23 0.00 3.0e-01 0.092 6.0 2.6e-09 0.39 0.07 0.14 FALSE
3 GTEx Brain Cerebellum FOXO6 0.35 0.33 enet 21 0.36 1.2e-11 3.602 5.7 1.4e-08 -0.01 0.96 0.04 FALSE
4 GTEx Breast Mammary Tissue (Female) CTPS1 0.12 -0.01 lasso 4 -0.01 7.5e-01 7.348 6.7 2.7e-11 0.61 0.04 0.10 FALSE
5 GTEx Cells EBV-transformed lymphocytes CTPS1 0.26 0.11 lasso 6 0.08 1.6e-03 8.640 8.1 4.0e-16 0.70 0.20 0.34 FALSE
6 GTEx Lung CTPS1 0.06 0.04 lasso 3 0.04 2.4e-04 8.914 9.2 5.2e-20 0.77 0.21 0.63 FALSE
7 GTEx Nerve Tibial SCMH1 0.16 0.03 enet 24 0.07 1.6e-05 10.748 -10.0 1.5e-23 -0.70 0.02 0.97 FALSE
8 GTEx Testis SLFNL1 0.30 0.17 lasso 14 0.28 5.3e-13 10.789 7.8 4.0e-15 0.85 0.01 0.99 FALSE
9 GTEx Testis CTPS1 0.57 0.28 enet 17 0.38 1.0e-17 -3.077 5.3 8.6e-08 0.48 0.98 0.02 FALSE
10 ROSMAP Brain Pre-frontal Cortex CTPS1 0.04 0.04 enet 7 0.04 9.1e-06 7.361 5.3 1.0e-07 0.59 0.61 0.14 FALSE
11 The Cancer Genome Atlas Breast Invasive Carcinoma SLFNL1 0.03 0.01 enet 6 0.02 5.6e-05 -1.200 5.9 3.8e-09 0.58 0.12 0.71 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma SCMH1 0.04 0.01 enet 7 0.02 2.5e-03 -0.004 -7.7 1.4e-14 -0.70 0.01 0.79 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma SCMH1 0.03 0.03 lasso 2 0.02 6.2e-03 10.921 -10.9 9.1e-28 -1.00 0.01 0.95 FALSE
14 The Cancer Genome Atlas Testicular Germ Cell Tumors SCMH1 0.35 0.14 blup 96 0.14 1.5e-05 -4.433 5.8 8.4e-09 0.47 0.18 0.24 FALSE
15 The Cancer Genome Atlas Thyroid Carcinoma SCMH1 0.07 0.08 blup 97 0.07 2.5e-07 10.621 -12.5 1.2e-35 -0.75 0.05 0.95 TRUE