[Hub]/) : Traits : Arm fat-free mass (left) :

chr6:160,071,844-161,571,560

Best TWAS P=2.36e-11 · Best GWAS P=1.05e-14 conditioned to 2.21e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum SLC22A3 0.13 0.06 enet 7 0.09 1.3e-05 -5.3 -5.3 8.6e-08 -0.63 0.58 0.40 FALSE
2 GTEx Brain Caudate basal ganglia SLC22A3 0.15 0.10 enet 39 0.11 5.6e-04 -6.4 -6.7 2.4e-11 -0.71 0.06 0.86 TRUE
3 GTEx Brain Frontal Cortex BA9 SLC22A3 0.26 0.08 lasso 6 0.05 1.5e-02 -4.1 -5.6 2.1e-08 -0.62 0.14 0.62 FALSE
4 GTEx Esophagus Mucosa SLC22A3 0.19 0.08 enet 47 0.12 1.7e-08 5.4 -6.3 3.0e-10 -0.58 0.52 0.48 FALSE
5 GTEx Nerve Tibial SLC22A3 0.20 0.10 lasso 7 0.13 3.2e-09 -5.3 -5.7 1.1e-08 -0.56 0.99 0.00 FALSE
6 GTEx Skin Not Sun Exposed Suprapubic SLC22A3 0.15 0.05 lasso 9 0.05 9.9e-04 -3.0 -5.5 3.1e-08 -0.65 0.05 0.94 FALSE
7 ROSMAP Brain Pre-frontal Cortex SLC22A3 0.14 0.20 lasso 10 0.19 2.4e-24 -5.2 -5.6 2.8e-08 -0.67 1.00 0.00 FALSE
8 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma LPAL2 0.07 0.00 blup 74 0.04 1.1e-03 -3.5 5.4 5.9e-08 0.75 0.04 0.54 FALSE