[Hub]/) : Traits : Arm fat-free mass (left) : ← →

chr7:2,032,803-3,581,391

Best TWAS P=2.35e-27 · Best GWAS P=4.19e-26 conditioned to 0.0503

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
20	ROSMAP	Brain Pre-frontal Cortex	AMZ1	0.09	0.05	lasso	6	0.04	2.4e-06	-10.5	10.8	2.4e-27	-0.90	0.01	0.99	TRUE
4	GTEx	Cells EBV-transformed lymphocytes	GNA12	0.46	0.51	lasso	5	0.50	7.9e-19	-10.6	-10.5	1.1e-25	0.99	0.00	1.00	FALSE
17	GTEx	Whole Blood	GNA12	0.09	0.01	enet	4	0.00	3.3e-01	-10.1	-10.2	3.0e-24	0.94	0.02	0.92	FALSE
10	GTEx	Esophagus Muscularis	GNA12	0.32	0.31	lasso	3	0.34	2.1e-21	-10.5	-10.1	7.0e-24	0.94	0.00	1.00	FALSE
22	The Cancer Genome Atlas	Esophageal Carcinoma	AMZ1	0.18	0.05	blup	69	0.05	1.4e-02	6.9	-9.6	1.3e-21	0.71	0.01	0.70	FALSE
9	GTEx	Esophagus Mucosa	GNA12	0.16	0.13	lasso	3	0.13	3.0e-09	-10.3	-9.4	8.3e-21	0.87	0.02	0.98	FALSE
3	GTEx	Artery Tibial	GNA12	0.24	0.13	enet	20	0.22	3.5e-17	-10.5	-8.8	9.6e-19	0.84	0.02	0.98	FALSE
8	GTEx	Esophagus Gastroesophageal Junction	GNA12	0.20	0.12	lasso	6	0.12	3.4e-05	-6.1	-8.6	1.3e-17	0.86	0.04	0.95	FALSE
6	GTEx	Colon Sigmoid	GNA12	0.14	0.05	lasso	3	0.03	3.6e-02	-6.1	-8.5	1.4e-17	0.87	0.02	0.92	FALSE
25	The Cancer Genome Atlas	Lung Adenocarcinoma	GNA12	0.03	0.01	enet	7	0.02	1.5e-03	4.1	-8.5	2.8e-17	0.78	0.06	0.74	FALSE
5	GTEx	Cells Transformed fibroblasts	GNA12	0.21	0.11	lasso	11	0.15	1.7e-11	-10.5	-8.3	8.8e-17	0.86	0.02	0.98	FALSE
12	GTEx	Nerve Tibial	GNA12	0.31	0.34	lasso	7	0.36	9.6e-27	-6.2	-8.3	1.0e-16	0.86	0.77	0.23	FALSE
14	GTEx	Skin Sun Exposed Lower leg	GNA12	0.17	0.16	lasso	3	0.18	1.3e-14	-6.0	-8.2	1.8e-16	0.87	0.12	0.88	FALSE
11	GTEx	Lung	GNA12	0.16	0.08	enet	21	0.12	1.2e-09	-10.2	-8.1	6.3e-16	0.78	0.01	0.99	FALSE
24	The Cancer Genome Atlas	Brain Lower Grade Glioma	AMZ1	0.04	0.04	lasso	3	0.02	1.3e-03	6.9	7.9	2.3e-15	-0.60	0.03	0.92	FALSE
19	NTR	Blood	GNA12	0.07	0.03	bslmm	597	0.06	1.3e-17	-7.7	-7.6	3.8e-14	0.63	0.90	0.10	FALSE
21	YFS	Blood	GNA12	0.23	0.15	bslmm	570	0.25	4.5e-82	5.5	-7.1	1.4e-12	0.52	1.00	0.00	FALSE
2	GTEx	Adipose Subcutaneous	GNA12	0.11	0.08	lasso	4	0.07	1.3e-06	-6.1	-6.9	6.0e-12	0.76	0.13	0.87	FALSE
1	CommonMind	Brain Pre-frontal Cortex	AMZ1	0.19	0.12	enet	22	0.13	5.7e-16	5.4	6.8	9.9e-12	-0.43	1.00	0.00	FALSE
15	GTEx	Small Intestine Terminal Ileum	GNA12	0.34	0.20	lasso	5	0.16	2.4e-04	-6.2	-6.8	1.0e-11	0.72	0.06	0.81	FALSE
18	METSIM	Adipose	GNA12	0.07	0.05	lasso	3	0.05	3.3e-08	-6.2	-6.3	3.9e-10	0.72	0.26	0.74	FALSE
16	GTEx	Stomach	GNA12	0.18	0.16	lasso	2	0.13	6.6e-07	-6.1	-6.2	6.6e-10	0.70	0.30	0.69	FALSE
23	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GNA12	0.03	0.04	lasso	1	0.04	3.0e-05	-6.1	-6.1	9.5e-10	0.72	0.07	0.78	FALSE
7	GTEx	Colon Transverse	GNA12	0.19	0.08	lasso	4	0.10	2.3e-05	5.1	-5.8	7.0e-09	0.58	0.29	0.68	FALSE
13	GTEx	Skin Not Sun Exposed Suprapubic	GNA12	0.10	0.15	lasso	3	0.12	4.2e-07	4.7	-5.2	1.9e-07	0.54	0.31	0.67	FALSE