Best TWAS P=3.11e-14 · Best GWAS P=3.55e-15 conditioned to 0.00367
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | CCDC126 | 0.12 | 0.03 | lasso | 7 | 0.01 | 0.043 | -6.2 | 5.7 | 1.1e-08 | -0.51 | 0.12 | 0.39 | FALSE |
| 2 | The Cancer Genome Atlas | Esophageal Carcinoma | TRA2A | 0.18 | 0.02 | blup | 40 | 0.05 | 0.012 | -7.4 | -7.6 | 3.1e-14 | 0.82 | 0.01 | 0.40 | TRUE |
| 3 | The Cancer Genome Atlas | Soft Tissue Sarcoma | RPS2P32 | 0.08 | 0.02 | blup | 27 | 0.02 | 0.031 | -4.7 | 5.2 | 1.6e-07 | -0.45 | 0.03 | 0.14 | FALSE |