[Hub]/) : Traits : Arm fat-free mass (left) :

chr7:70,996,097-73,789,730

Best TWAS P=3.06e-15 · Best GWAS P=2.45e-15 conditioned to 0.0494

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DNAJC30 0.13 0.07 enet 32 0.07 2.7e-09 5.569 5.9 4.3e-09 0.36 1.00 0.00 TRUE
2 GTEx Adipose Subcutaneous MLXIPL 0.11 0.07 enet 16 0.07 1.6e-06 7.054 7.6 2.4e-14 0.70 0.08 0.92 FALSE
3 GTEx Adipose Visceral Omentum MLXIPL 0.16 0.02 lasso 3 0.03 7.8e-03 6.976 7.4 1.7e-13 0.67 0.27 0.70 FALSE
4 GTEx Adipose Visceral Omentum NSUN5 0.07 0.03 enet 11 0.04 4.0e-03 7.331 6.3 3.5e-10 0.48 0.03 0.65 FALSE
5 GTEx Cells Transformed fibroblasts MLXIPL 0.13 0.06 enet 6 0.09 2.2e-07 7.571 7.8 5.4e-15 0.77 0.09 0.91 FALSE
6 GTEx Heart Left Ventricle MLXIPL 0.14 0.00 enet 24 0.01 1.3e-01 0.045 5.2 1.5e-07 0.38 0.16 0.19 FALSE
7 GTEx Lung MLXIPL 0.10 0.07 enet 14 0.07 6.3e-06 7.054 5.5 5.1e-08 0.50 0.22 0.46 FALSE
8 GTEx Skin Not Sun Exposed Suprapubic MLXIPL 0.11 0.11 lasso 3 0.06 2.7e-04 7.571 7.5 7.1e-14 0.62 0.06 0.89 FALSE
9 GTEx Skin Sun Exposed Lower leg MLXIPL 0.12 0.09 lasso 4 0.06 6.1e-06 7.545 7.7 1.6e-14 0.69 0.09 0.91 FALSE
10 GTEx Spleen NCF1B 0.22 0.10 enet 9 0.08 5.1e-03 7.471 -7.5 8.8e-14 -0.88 0.02 0.58 FALSE
11 GTEx Testis MLXIPL 0.10 0.00 lasso 3 0.00 3.3e-01 4.956 6.8 9.1e-12 0.58 0.05 0.15 FALSE
12 GTEx Testis VPS37D 0.15 0.01 lasso 5 0.03 2.7e-02 -4.892 -5.3 1.5e-07 -0.33 0.13 0.05 FALSE
13 GTEx Thyroid MLXIPL 0.23 0.14 lasso 7 0.15 2.1e-11 7.054 7.9 3.1e-15 0.73 0.10 0.90 TRUE
14 METSIM Adipose BCL7B 0.10 0.02 enet 20 0.05 1.2e-07 6.976 5.5 4.9e-08 0.20 0.04 0.96 FALSE
15 METSIM Adipose MLXIPL 0.12 0.14 lasso 4 0.13 1.8e-19 7.303 7.8 6.2e-15 0.80 0.31 0.69 FALSE
16 The Cancer Genome Atlas Breast Invasive Carcinoma MLXIPL 0.06 0.05 lasso 2 0.05 5.1e-10 7.307 6.9 4.6e-12 0.77 0.02 0.98 FALSE
17 The Cancer Genome Atlas Lung Adenocarcinoma MLXIPL 0.04 0.03 lasso 1 0.02 2.3e-03 7.307 7.3 2.7e-13 0.83 0.01 0.72 FALSE
18 The Cancer Genome Atlas Prostate Adenocarcinoma MLXIPL 0.08 0.05 enet 4 0.05 5.3e-06 7.307 6.2 5.9e-10 0.70 0.02 0.94 FALSE
19 The Cancer Genome Atlas Skin Cutaneous Melanoma CALN1 0.37 0.04 enet 10 0.25 3.1e-07 -6.345 5.3 1.4e-07 0.05 0.01 0.96 TRUE
20 The Cancer Genome Atlas Thyroid Carcinoma BCL7B 0.05 0.01 blup 5 0.03 1.3e-03 7.307 -6.8 1.1e-11 -0.93 0.00 0.63 FALSE