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Traits
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Arm fat-free mass (left)
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chr1:71,163,715-73,435,171
Best TWAS P=3.21e-09 · Best GWAS P=1.15e-14 conditioned to 2.72e-08
71.5M
72M
72.5M
73M
73.5M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
ROSMAP
Brain Pre-frontal Cortex
NEGR1
0.24
0.15
lasso
8
0.22
1.3e-27
4.6
5.9
3.2e-09
-0.48
0.97
0.03
TRUE
1
GTEx
Esophagus Muscularis
NEGR1
0.13
0.04
lasso
3
0.05
5.1e-04
-4.6
5.1
2.9e-07
-0.66
0.72
0.10
FALSE