Best TWAS P=3.21e-09 · Best GWAS P=1.15e-14 conditioned to 2.72e-08
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Muscularis | NEGR1 | 0.13 | 0.04 | lasso | 3 | 0.05 | 5.1e-04 | -4.6 | 5.1 | 2.9e-07 | -0.66 | 0.72 | 0.10 | FALSE |
2 | ROSMAP | Brain Pre-frontal Cortex | NEGR1 | 0.24 | 0.15 | lasso | 8 | 0.22 | 1.3e-27 | 4.6 | 5.9 | 3.2e-09 | -0.48 | 0.97 | 0.03 | TRUE |