Best TWAS P=3.99e-08 · Best GWAS P=9.07e-10 conditioned to 0.000217
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Muscle Skeletal | KCTD9 | 0.11 | 0.07 | lasso | 5 | 0.06 | 7.9e-07 | -5.1 | -5.5 | 4e-08 | -0.56 | 0.16 | 0.84 | TRUE |
2 | The Cancer Genome Atlas | Lung Adenocarcinoma | KCTD9 | 0.03 | 0.01 | blup | 75 | 0.01 | 1.1e-02 | -5.6 | -5.5 | 4e-08 | -0.45 | 0.03 | 0.61 | FALSE |