[Hub]/) : Traits : Arm fat-free mass (left) : ← →

chr8:56,269,387-57,683,880

Best TWAS P=7.85e-23 · Best GWAS P=2.34e-39 conditioned to 1.42e-18

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial RP11-446E9.1 0.07 0.00 lasso 6 0.00 6.6e-01 -6.1 7.2 8.3e-13 -0.76 0.02 0.74 FALSE
2 GTEx Brain Cerebellum RPS20 0.26 0.07 enet 17 0.10 5.4e-04 -8.4 -7.7 1.8e-14 0.60 0.26 0.33 FALSE
3 GTEx Brain Cerebellum RP11-446E9.1 0.15 0.05 lasso 3 0.03 3.7e-02 -5.9 5.7 1.0e-08 -0.53 0.05 0.54 FALSE
4 GTEx Brain Nucleus accumbens basal ganglia RPS20 0.41 0.05 lasso 8 0.13 3.1e-04 -6.3 -5.9 2.9e-09 0.53 0.05 0.26 FALSE
5 GTEx Esophagus Muscularis RPS20 0.12 0.04 lasso 6 0.05 7.2e-04 -8.5 -8.4 4.0e-17 0.76 0.21 0.65 FALSE
6 GTEx Muscle Skeletal RPS20 0.07 0.09 lasso 1 0.07 1.5e-07 -5.8 -5.8 7.4e-09 0.49 0.98 0.02 FALSE
7 GTEx Skin Not Sun Exposed Suprapubic RPS20 0.18 0.03 enet 12 0.07 1.5e-04 -8.1 -9.8 7.8e-23 0.81 0.12 0.58 TRUE
8 GTEx Stomach RP11-446E9.1 0.12 0.08 lasso 4 0.03 1.7e-02 -5.3 5.3 1.5e-07 -0.48 0.30 0.10 FALSE
9 ROSMAP Brain Pre-frontal Cortex RPS20 0.24 0.20 lasso 6 0.23 3.4e-29 -7.4 -6.6 3.8e-11 0.51 1.00 0.00 FALSE
10 ROSMAP Brain Pre-frontal Cortex RP11-446E9.1 0.23 0.32 lasso 7 0.34 2.0e-45 -5.8 6.7 1.9e-11 -0.53 1.00 0.00 FALSE
11 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma RPS20 0.04 0.02 blup 29 0.03 4.8e-04 -7.2 -6.7 2.4e-11 0.49 0.03 0.03 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma RPS20 0.33 0.07 enet 8 0.07 1.7e-08 -7.4 -8.5 1.4e-17 0.49 0.96 0.03 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma RPS20 0.04 0.03 lasso 3 0.04 1.3e-04 -7.4 -7.3 2.2e-13 0.58 0.15 0.05 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma LYN 0.09 0.12 lasso 2 0.12 8.4e-12 -5.3 5.4 7.5e-08 -0.49 1.00 0.00 FALSE