Best TWAS P=5.76e-08 · Best GWAS P=4.66e-07 conditioned to 0.0186
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | POLR2L | 0.03 | 0.02 | bslmm | 413 | 0.01 | 0.00496 | -2.3 | -5.4 | 5.8e-08 | 0.57 | 0.14 | 0.10 | TRUE |
2 | The Cancer Genome Atlas | Lung Adenocarcinoma | TSPAN4 | 0.09 | 0.04 | enet | 9 | 0.03 | 0.00019 | 3.3 | 5.2 | 1.8e-07 | -0.43 | 0.16 | 0.38 | FALSE |