[Hub]/) : Traits : Arm fat-free mass (left) : ← →

chr10:123,438,113-124,889,817

Best TWAS P=6.46e-12 · Best GWAS P=9.56e-12 conditioned to 0.0293

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PLEKHA1 0.14 0.06 lasso 2 0.03 2.4e-03 6.5 -6.5 6.5e-11 0.76 0.05 0.93 FALSE
2 GTEx Muscle Skeletal PLEKHA1 0.10 0.04 lasso 3 0.04 8.2e-05 -6.7 -5.3 1.0e-07 0.86 0.02 0.98 FALSE
3 GTEx Nerve Tibial PLEKHA1 0.22 0.23 enet 17 0.19 1.1e-13 6.5 -5.8 5.7e-09 0.64 0.05 0.95 FALSE
4 GTEx Skin Sun Exposed Lower leg PLEKHA1 0.16 0.02 lasso 5 0.01 4.0e-02 -5.4 -6.0 2.3e-09 0.81 0.02 0.96 FALSE
5 METSIM Adipose PLEKHA1 0.05 0.03 lasso 4 0.04 3.6e-07 6.4 -6.9 6.5e-12 0.80 0.04 0.96 TRUE
6 ROSMAP Brain Pre-frontal Cortex PLEKHA1 0.06 0.05 lasso 4 0.05 1.3e-06 -6.6 -6.7 3.0e-11 0.99 0.01 0.99 FALSE
7 The Cancer Genome Atlas Brain Lower Grade Glioma PLEKHA1 0.04 0.05 lasso 2 0.04 4.3e-05 6.5 -6.4 1.3e-10 0.77 0.04 0.95 FALSE
8 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma ARMS2 0.23 0.20 lasso 2 0.21 7.0e-09 -5.4 -5.7 1.6e-08 0.65 0.80 0.14 FALSE
9 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma PLEKHA1 0.08 0.06 blup 103 0.02 4.0e-02 6.4 -5.5 4.8e-08 0.83 0.02 0.82 FALSE
10 The Cancer Genome Atlas Prostate Adenocarcinoma ARMS2 0.06 0.04 blup 71 0.05 4.9e-06 -6.6 -6.4 1.5e-10 0.81 0.00 0.99 FALSE
11 The Cancer Genome Atlas Thyroid Carcinoma PLEKHA1 0.08 0.10 lasso 1 0.09 3.5e-09 6.4 -6.4 1.6e-10 0.77 0.06 0.94 FALSE