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Traits
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Arm fat-free mass (left)
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chr12:93,110,493-94,675,142
Best TWAS P=7.49e-19 · Best GWAS P=2.96e-41 conditioned to 1.4e-21
93.2M
93.4M
93.6M
93.8M
94M
94.2M
94.4M
94.6M
0
10
20
30
40
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Breast Mammary Tissue (Male)
MRPL42
0.21
-0.01
lasso
2
-0.01
6.0e-01
9.0
-8.9
7.5e-19
-0.48
0.05
0.06
TRUE
3
YFS
Blood
SOCS2
0.06
0.04
bslmm
444
0.04
1.7e-12
5.5
7.0
2.5e-12
0.01
1.00
0.00
TRUE
2
GTEx
Muscle Skeletal
MRPL42
0.07
0.02
lasso
3
0.04
1.5e-04
-5.1
-5.4
7.0e-08
-0.17
0.69
0.01
TRUE
4
YFS
Blood
UBE2N
0.02
0.00
bslmm
424
0.01
3.6e-03
11.4
5.3
1.4e-07
0.38
0.06
0.27
FALSE