[Hub]/) : Traits : Arm fat-free mass (left) :

chr14:24,098,631-25,546,115

Best TWAS P=3.36e-12 · Best GWAS P=2.13e-11 conditioned to 0.102

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Heart Atrial Appendage ADCY4 0.28 0.14 lasso 4 0.10 2.1e-05 6.4 5.3 9.2e-08 0.36 0.02 0.96 TRUE
2 GTEx Spleen NFATC4 0.45 0.00 enet 24 0.00 2.5e-01 3.9 -5.6 2.2e-08 -0.25 0.06 0.06 TRUE
3 GTEx Thyroid ADCY4 0.13 0.13 lasso 6 0.09 1.0e-07 4.0 5.2 1.7e-07 0.60 0.11 0.89 FALSE
4 METSIM Adipose ADCY4 0.07 0.03 lasso 5 0.03 2.2e-05 6.6 7.0 3.4e-12 0.66 0.01 0.99 TRUE
5 The Cancer Genome Atlas Bladder Urothelial Carcinoma ADCY4 0.03 0.01 blup 75 0.03 1.1e-03 4.2 5.4 8.0e-08 0.66 0.04 0.81 FALSE
6 The Cancer Genome Atlas Colon Adenocarcinoma ADCY4 0.07 0.02 lasso 4 0.03 4.7e-03 4.6 5.4 8.4e-08 0.67 0.03 0.76 TRUE
7 The Cancer Genome Atlas Brain Lower Grade Glioma ADCY4 0.06 0.06 lasso 6 0.09 3.0e-10 5.8 6.7 2.1e-11 0.71 0.02 0.98 FALSE
8 The Cancer Genome Atlas Lung Adenocarcinoma ADCY4 0.07 0.09 lasso 3 0.08 4.4e-10 4.8 5.9 3.3e-09 0.61 0.86 0.14 FALSE
9 The Cancer Genome Atlas Stomach Adenocarcinoma LTB4R2 0.04 0.04 lasso 1 0.02 2.5e-02 5.4 -5.4 6.4e-08 -0.77 0.04 0.52 FALSE