[Hub]/) : Traits : Arm fat-free mass (left) : ← →

chr14:24,098,631-25,546,115

Best TWAS P=3.36e-12 · Best GWAS P=2.13e-11 conditioned to 0.102

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	METSIM	Adipose	ADCY4	0.07	0.03	lasso	5	0.03	2.2e-05	6.6	7.0	3.4e-12	0.66	0.01	0.99	TRUE
2	GTEx	Spleen	NFATC4	0.45	0.00	enet	24	0.00	2.5e-01	3.9	-5.6	2.2e-08	-0.25	0.06	0.06	TRUE
6	The Cancer Genome Atlas	Colon Adenocarcinoma	ADCY4	0.07	0.02	lasso	4	0.03	4.7e-03	4.6	5.4	8.4e-08	0.67	0.03	0.76	TRUE
1	GTEx	Heart Atrial Appendage	ADCY4	0.28	0.14	lasso	4	0.10	2.1e-05	6.4	5.3	9.2e-08	0.36	0.02	0.96	TRUE
7	The Cancer Genome Atlas	Brain Lower Grade Glioma	ADCY4	0.06	0.06	lasso	6	0.09	3.0e-10	5.8	6.7	2.1e-11	0.71	0.02	0.98	FALSE
8	The Cancer Genome Atlas	Lung Adenocarcinoma	ADCY4	0.07	0.09	lasso	3	0.08	4.4e-10	4.8	5.9	3.3e-09	0.61	0.86	0.14	FALSE
9	The Cancer Genome Atlas	Stomach Adenocarcinoma	LTB4R2	0.04	0.04	lasso	1	0.02	2.5e-02	5.4	-5.4	6.4e-08	-0.77	0.04	0.52	FALSE
5	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	ADCY4	0.03	0.01	blup	75	0.03	1.1e-03	4.2	5.4	8.0e-08	0.66	0.04	0.81	FALSE
3	GTEx	Thyroid	ADCY4	0.13	0.13	lasso	6	0.09	1.0e-07	4.0	5.2	1.7e-07	0.60	0.11	0.89	FALSE