[Hub]/) : Traits : Arm fat-free mass (left) :

chr14:34,480,400-36,571,554

Best TWAS P=3.43e-12 · Best GWAS P=3.95e-10 conditioned to 0.204

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PPP2R3C 0.21 0.12 lasso 10 0.14 2.6e-11 -6.3 5.9 4.4e-09 -0.95 0.00 1.00 FALSE
2 GTEx Artery Tibial RP11-85K15.2 0.06 0.01 lasso 6 0.02 2.1e-02 -5.9 -6.0 2.1e-09 0.67 0.04 0.79 FALSE
3 GTEx Cells Transformed fibroblasts PPP2R3C 0.31 0.10 lasso 10 0.18 4.0e-13 -6.3 6.0 2.1e-09 -0.87 0.00 1.00 FALSE
4 GTEx Cells Transformed fibroblasts CFL2 0.14 0.08 enet 39 0.11 9.9e-09 -1.8 -7.0 3.4e-12 0.30 0.59 0.04 TRUE
5 GTEx Thyroid FAM177A1 0.13 0.04 enet 18 0.07 5.5e-06 -5.1 5.3 1.5e-07 -0.75 0.09 0.91 FALSE
6 NTR Blood KIAA0391 0.05 0.05 lasso 10 0.05 2.4e-15 -6.3 -5.1 2.6e-07 0.94 0.00 1.00 FALSE
7 NTR Blood NFKBIA 0.26 0.09 lasso 10 0.12 3.4e-36 -4.0 -5.9 3.9e-09 0.42 1.00 0.00 FALSE
8 YFS Blood KIAA0391 0.29 0.36 lasso 7 0.38 5.8e-132 -6.3 -6.1 1.0e-09 0.99 0.00 1.00 FALSE
9 YFS Blood NFKBIA 0.24 0.11 enet 33 0.17 3.5e-53 -3.8 -6.2 7.0e-10 0.51 1.00 0.00 TRUE
10 YFS Blood PPP2R3C 0.53 0.46 bslmm 383 0.60 2.4e-254 3.8 -5.7 1.5e-08 0.63 1.00 0.00 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma KIAA0391 0.07 0.04 blup 110 0.04 1.9e-05 -3.7 5.5 3.4e-08 -0.83 0.04 0.96 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma PPP2R3C 0.08 0.04 blup 51 0.07 7.8e-09 -5.0 6.4 1.7e-10 -0.82 0.01 0.99 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma KIAA0391 0.12 0.11 enet 14 0.14 2.0e-13 -4.5 5.6 1.9e-08 -0.77 0.63 0.36 FALSE