Best TWAS P=1.27e-08 · Best GWAS P=5.1e-10 conditioned to 0.00468
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | BTBD7 | 0.16 | 0.01 | lasso | 8 | 0.04 | 0.00036 | -5.8 | 5.7 | 1.4e-08 | -0.62 | 0.07 | 0.92 | FALSE |
| 2 | The Cancer Genome Atlas | Lung Adenocarcinoma | RIN3 | 0.05 | 0.00 | blup | 163 | 0.01 | 0.06020 | -2.8 | -5.2 | 1.6e-07 | 0.06 | 0.02 | 0.12 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | BTBD7 | 0.02 | 0.01 | blup | 72 | 0.02 | 0.00677 | -5.5 | 5.3 | 1.4e-07 | -0.69 | 0.01 | 0.88 | FALSE |
| 4 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | BTBD7 | 0.11 | 0.03 | blup | 72 | 0.02 | 0.07950 | -5.8 | 5.7 | 1.3e-08 | -0.67 | 0.02 | 0.80 | TRUE |