Best TWAS P=4.81e-11 · Best GWAS P=1.96e-11 conditioned to 0.0564
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | RPS6KA5 | 0.08 | 0.07 | lasso | 2 | 0.06 | 5.3e-05 | -6.4 | 6.6 | 4.8e-11 | -0.89 | 0.02 | 0.98 | TRUE |
| 2 | GTEx | Spleen | C14orf159 | 0.30 | 0.21 | lasso | 5 | 0.21 | 3.6e-06 | -5.4 | 6.1 | 9.2e-10 | -0.81 | 0.08 | 0.40 | FALSE |