TWAS
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Traits
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Traits
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Arm fat-free mass (left)
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chr15:65,974,936-68,789,191
Best TWAS P=2.77e-08 · Best GWAS P=1.77e-13 conditioned to 1.82e-12
66M
66.5M
67M
67.5M
68M
68.5M
0
5
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Adipose Visceral Omentum
RPL9P25
0.26
0.02
enet
27
0.07
1.3e-04
-2.8
-5.6
2.8e-08
-0.10
0.72
0.02
TRUE
3
GTEx
Muscle Skeletal
MAP2K5
0.08
0.03
lasso
6
0.05
1.9e-05
4.4
5.4
7.5e-08
-0.02
0.01
0.99
TRUE
2
GTEx
Colon Transverse
IQCH-AS1
0.24
0.01
enet
31
0.08
1.5e-04
-6.6
-5.2
2.2e-07
0.03
0.03
0.92
TRUE
4
The Cancer Genome Atlas
Soft Tissue Sarcoma
LBXCOR1
0.07
0.03
blup
57
0.03
6.3e-03
-5.5
5.4
8.0e-08
-0.01
0.02
0.48
FALSE