[Hub]/) : Traits : Arm fat-free mass (left) :

chr16:14,229,099-15,886,243

Best TWAS P=5.3e-12 · Best GWAS P=6.67e-09 conditioned to 0.287

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous NTAN1 0.05 0.03 lasso 2 0.04 6.7e-04 -5.7 6.3 2.8e-10 0.69 0.01 0.96 FALSE
2 GTEx Artery Tibial RRN3 0.11 0.06 lasso 2 0.07 2.0e-06 5.8 5.5 3.2e-08 0.99 0.01 0.99 FALSE
3 GTEx Cells EBV-transformed lymphocytes RRN3 0.36 0.14 lasso 5 0.20 4.5e-07 5.8 6.0 2.3e-09 0.97 0.01 0.99 FALSE
4 GTEx Cells EBV-transformed lymphocytes RP11-958N24.1 0.22 0.02 lasso 5 0.06 4.8e-03 -2.5 5.2 1.8e-07 0.72 0.01 0.56 FALSE
5 GTEx Cells Transformed fibroblasts RRN3 0.10 0.12 enet 13 0.13 6.3e-10 5.8 6.4 2.0e-10 0.95 0.01 0.99 FALSE
6 GTEx Colon Transverse RRN3 0.13 0.00 lasso 5 0.00 1.9e-01 5.6 -5.7 9.7e-09 -0.68 0.02 0.57 FALSE
7 GTEx Esophagus Mucosa RRN3 0.13 0.13 lasso 4 0.13 3.2e-09 5.6 5.4 7.4e-08 0.98 0.01 0.99 FALSE
8 GTEx Heart Atrial Appendage NOMO1 0.19 0.12 lasso 6 0.10 3.7e-05 5.6 5.6 2.7e-08 0.98 0.01 0.96 FALSE
9 GTEx Heart Atrial Appendage NTAN1 0.10 0.09 lasso 1 0.07 3.7e-04 5.6 5.6 2.4e-08 1.00 0.01 0.87 FALSE
10 GTEx Heart Left Ventricle RRN3 0.24 0.12 lasso 7 0.17 2.2e-09 5.6 -6.6 4.7e-11 -0.87 0.01 0.99 FALSE
11 GTEx Heart Left Ventricle NTAN1 0.09 0.04 lasso 3 0.02 2.0e-02 5.8 5.7 1.0e-08 0.99 0.01 0.87 FALSE
12 GTEx Muscle Skeletal RRN3 0.18 0.03 enet 17 0.11 5.7e-11 4.5 -5.8 5.4e-09 -0.49 0.16 0.72 FALSE
13 GTEx Muscle Skeletal NTAN1 0.12 0.07 lasso 6 0.09 1.4e-09 5.6 6.2 6.2e-10 0.90 0.01 0.99 FALSE
14 GTEx Nerve Tibial NTAN1 0.07 0.00 enet 14 0.00 1.7e-01 5.8 6.5 6.8e-11 0.46 0.01 0.36 FALSE
15 GTEx Skin Sun Exposed Lower leg RRN3 0.10 0.12 lasso 1 0.11 4.5e-09 5.8 5.8 6.7e-09 1.00 0.01 0.99 FALSE
16 GTEx Testis RRN3 0.10 0.10 lasso 2 0.07 3.9e-04 5.8 5.8 6.7e-09 1.00 0.01 0.94 FALSE
17 METSIM Adipose NTAN1 0.07 0.06 enet 12 0.06 1.7e-09 5.8 5.2 1.6e-07 0.88 0.01 0.99 FALSE
18 NTR Blood NTAN1 0.01 0.00 bslmm 110 0.00 4.2e-02 5.8 6.2 4.8e-10 0.72 0.01 0.47 FALSE
19 NTR Blood PDXDC1 0.12 0.12 enet 26 0.15 1.3e-46 -5.6 6.9 5.3e-12 0.74 0.01 0.99 TRUE
20 ROSMAP Brain Pre-frontal Cortex NTAN1 0.12 0.10 lasso 3 0.11 1.4e-13 5.6 5.7 1.4e-08 0.97 0.01 0.99 FALSE