[Hub]/) : Traits : Arm fat-free mass (left) :

chr16:19,022,448-21,352,507

Best TWAS P=1.47e-11 · Best GWAS P=8.64e-11 conditioned to 1.11e-06

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous GPRC5B 0.07 0.04 lasso 4 0.03 1.3e-03 -6.1 6.8 1.5e-11 0.31 0.08 0.78 TRUE
2 GTEx Cells Transformed fibroblasts THUMPD1 0.13 0.16 enet 16 0.16 4.2e-12 -5.1 -5.3 1.4e-07 0.04 0.16 0.84 FALSE
3 GTEx Esophagus Gastroesophageal Junction KNOP1 0.51 0.44 enet 22 0.56 5.3e-24 -4.5 -5.3 1.1e-07 -0.27 0.71 0.29 FALSE
4 GTEx Esophagus Gastroesophageal Junction AC002550.5 0.62 0.54 enet 35 0.63 4.4e-29 -3.7 -5.5 4.8e-08 -0.27 0.99 0.01 FALSE
5 GTEx Testis AC004381.6 0.18 0.10 lasso 7 0.08 1.8e-04 -5.2 -5.3 1.3e-07 0.04 0.12 0.72 TRUE
6 The Cancer Genome Atlas Lung Squamous Cell Carcinoma IQCK 0.03 0.03 lasso 3 0.02 7.2e-04 -5.2 -5.5 3.1e-08 -0.25 0.04 0.92 FALSE
7 The Cancer Genome Atlas Thyroid Carcinoma ACSM3 0.06 0.04 blup 43 0.03 5.9e-04 -5.2 5.2 1.9e-07 -0.05 0.01 0.96 FALSE
8 The Cancer Genome Atlas Thyroid Carcinoma GPRC5B 0.06 0.01 blup 38 0.01 2.4e-02 -3.7 -6.0 2.2e-09 -0.43 0.01 0.10 FALSE