Best TWAS P=5.1e-08 · Best GWAS P=1.57e-07 conditioned to 0.117
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | MLX | 0.03 | 0.03 | enet | 12 | 0.02 | 6.5e-04 | -5.2 | -5.2 | 2.5e-07 | 0.94 | 0.02 | 0.97 | FALSE |
| 2 | GTEx | Adipose Subcutaneous | HSD17B1P1 | 0.06 | 0.09 | enet | 6 | 0.09 | 4.0e-08 | -4.9 | -5.4 | 5.3e-08 | 0.92 | 0.03 | 0.97 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | NAGLU | 0.08 | 0.06 | enet | 9 | 0.09 | 5.8e-08 | 4.0 | -5.3 | 1.4e-07 | 0.84 | 0.02 | 0.97 | FALSE |
| 4 | The Cancer Genome Atlas | Colon Adenocarcinoma | CNTNAP1 | 0.06 | 0.05 | blup | 27 | 0.03 | 7.3e-03 | -5.0 | 5.3 | 1.4e-07 | -0.95 | 0.01 | 0.93 | FALSE |
| 5 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | NAGLU | 0.13 | 0.02 | enet | 8 | 0.04 | 1.6e-05 | 4.0 | -5.5 | 5.1e-08 | 0.78 | 0.01 | 0.86 | TRUE |