[Hub]/) : Traits : Arm fat-free mass (left) : ← →

chr20:19,649,716-21,919,054

Best TWAS P=5.91e-15 · Best GWAS P=1.68e-16 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex INSM1 0.07 0.00 bslmm 522 0.02 2.2e-03 4.13 5.4 5.6e-08 -0.01 0.09 0.08 TRUE
2 CommonMind Brain Pre-frontal Cortex PLK1S1 0.08 0.01 lasso 3 0.04 1.1e-05 6.34 6.2 7.4e-10 0.82 0.02 0.98 FALSE
3 GTEx Artery Tibial PLK1S1 0.07 0.08 enet 10 0.08 4.0e-07 8.11 7.8 5.9e-15 0.97 0.01 0.98 TRUE
4 GTEx Esophagus Mucosa PLK1S1 0.11 0.11 lasso 5 0.09 7.8e-07 6.27 6.2 4.6e-10 0.83 0.12 0.88 FALSE
5 GTEx Heart Atrial Appendage PLK1S1 0.15 -0.01 lasso 4 0.00 6.1e-01 0.85 5.4 7.0e-08 0.56 0.05 0.41 FALSE
6 GTEx Skin Not Sun Exposed Suprapubic PLK1S1 0.21 0.09 lasso 6 0.12 5.3e-07 7.75 6.6 3.2e-11 0.93 0.07 0.93 FALSE
7 GTEx Skin Sun Exposed Lower leg PLK1S1 0.15 0.13 enet 10 0.15 3.9e-12 6.22 5.7 9.9e-09 0.83 0.89 0.11 FALSE
8 GTEx Testis PLK1S1 0.64 0.34 enet 33 0.39 1.0e-18 6.22 6.6 4.9e-11 0.79 0.69 0.31 FALSE
9 GTEx Whole Blood PLK1S1 0.08 0.04 enet 9 0.02 4.0e-03 6.22 6.9 3.8e-12 0.89 0.06 0.93 FALSE
10 The Cancer Genome Atlas Breast Invasive Carcinoma PLK1S1 0.05 0.07 enet 9 0.07 5.5e-15 5.99 6.7 2.1e-11 0.88 0.15 0.85 FALSE
11 The Cancer Genome Atlas Lung Adenocarcinoma PLK1S1 0.04 0.03 blup 64 0.04 4.0e-05 6.22 7.2 4.5e-13 0.88 0.11 0.88 FALSE
12 The Cancer Genome Atlas Pancreatic Adenocarcinoma PLK1S1 0.09 0.02 blup 64 0.05 3.1e-03 6.34 7.2 4.9e-13 0.78 0.03 0.54 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma PLK1S1 0.19 0.12 enet 14 0.13 4.3e-13 6.28 6.4 2.1e-10 0.80 0.88 0.12 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma PLK1S1 0.06 0.04 lasso 3 0.04 1.5e-04 6.28 6.4 1.4e-10 0.85 0.15 0.61 FALSE