[Hub]/) : Traits : Arm fat-free mass (left) : ← →

chr19:46,276,056-51,224,297

Best TWAS P=5.16e-12 · Best GWAS P=4.55e-24 conditioned to 1.76e-08

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
17	METSIM	Adipose	SAE1	0.12	0.04	lasso	5	0.07	1.7e-10	-5.0	-6.9	5.2e-12	0.61	0.61	0.39	TRUE
22	The Cancer Genome Atlas	Colon Adenocarcinoma	SNRNP70	0.05	0.02	lasso	3	0.02	2.9e-02	5.2	-6.4	1.4e-10	-0.02	0.01	0.74	TRUE
6	GTEx	Nerve Tibial	AP2A1	0.16	0.05	lasso	4	0.07	1.3e-05	-5.0	-6.1	1.1e-09	0.02	0.01	0.99	TRUE
24	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	GRLF1	0.04	0.04	blup	51	0.03	7.0e-05	4.4	5.6	1.8e-08	-0.04	0.44	0.07	TRUE
8	GTEx	Skin Not Sun Exposed Suprapubic	RASIP1	0.15	0.04	lasso	6	0.08	2.9e-05	-4.7	-5.5	3.2e-08	0.03	0.40	0.33	TRUE
9	GTEx	Skin Sun Exposed Lower leg	CCDC9	0.13	0.00	lasso	5	0.00	2.2e-01	2.3	-5.5	3.6e-08	0.23	0.11	0.21	TRUE
16	METSIM	Adipose	PNMAL1	0.24	0.27	bslmm	380	0.28	2.9e-41	5.0	5.2	1.9e-07	-0.01	0.00	1.00	TRUE
3	GTEx	Cells EBV-transformed lymphocytes	SAE1	0.21	0.09	lasso	3	0.07	2.0e-03	-4.9	-6.5	5.9e-11	0.77	0.06	0.67	FALSE
5	GTEx	Esophagus Mucosa	AP2A1	0.18	0.09	enet	8	0.13	7.7e-09	-4.7	-6.0	1.7e-09	-0.01	0.02	0.98	FALSE
20	The Cancer Genome Atlas	Breast Invasive Carcinoma	LIN7B	0.02	0.00	enet	7	0.02	5.1e-05	4.9	-6.0	2.7e-09	-0.04	0.01	0.92	FALSE
15	GTEx	Testis	NTN5	0.16	0.02	enet	23	0.06	9.6e-04	-3.5	-5.9	2.8e-09	-0.02	0.03	0.75	FALSE
18	YFS	Blood	SAE1	0.07	0.02	enet	18	0.05	3.6e-16	-8.2	-5.9	4.0e-09	0.56	0.99	0.01	FALSE
4	GTEx	Cells Transformed fibroblasts	TBC1D17	0.11	0.03	enet	23	0.04	6.5e-04	-4.6	5.7	9.5e-09	-0.02	0.04	0.95	FALSE
13	GTEx	Spleen	PPFIA3	0.25	0.23	lasso	4	0.21	3.9e-06	4.8	-5.7	1.4e-08	-0.01	0.21	0.53	FALSE
14	GTEx	Stomach	VRK3	0.10	-0.01	enet	10	-0.01	7.3e-01	3.6	5.7	1.5e-08	0.00	0.04	0.41	FALSE
1	CommonMind	Brain Pre-frontal Cortex	LIN7B	0.08	0.08	lasso	3	0.08	8.5e-10	-5.4	-5.4	6.0e-08	-0.04	0.02	0.98	FALSE
21	The Cancer Genome Atlas	Breast Invasive Carcinoma	NTN5	0.02	0.01	enet	11	0.01	7.6e-04	-3.7	-5.4	7.2e-08	0.00	0.04	0.73	FALSE
10	GTEx	Skin Sun Exposed Lower leg	NTN5	0.11	0.09	enet	18	0.05	6.2e-05	-3.6	-5.2	1.6e-07	0.02	0.82	0.15	FALSE
11	GTEx	Skin Sun Exposed Lower leg	AP2A1	0.15	0.08	enet	10	0.07	1.9e-06	-5.0	-5.2	2.0e-07	-0.01	0.01	0.99	FALSE
12	GTEx	Small Intestine Terminal Ileum	PNMAL1	0.40	0.00	enet	11	0.15	2.7e-04	5.0	5.2	2.1e-07	-0.01	0.01	0.61	FALSE
19	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	FUT2	0.05	0.01	blup	52	0.01	6.1e-02	-4.9	5.2	2.1e-07	0.01	0.02	0.51	FALSE
23	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	FUT2	0.10	0.01	blup	51	0.05	9.8e-04	-3.4	5.2	2.1e-07	-0.02	0.03	0.82	FALSE
2	CommonMind	Brain Pre-frontal Cortex	PNKP	0.15	0.16	enet	23	0.16	7.0e-19	-5.0	-5.2	2.3e-07	0.03	0.06	0.94	FALSE
7	GTEx	Pituitary	PPFIA3	0.49	0.35	enet	22	0.37	2.7e-10	-5.0	5.2	2.3e-07	0.00	0.25	0.74	FALSE