[Hub]/) : Traits : Arm fat-free mass (left) :

chr1:182,298,784-184,739,300

Best TWAS P=1.57e-13 · Best GWAS P=3.79e-13 conditioned to 0.00621

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex TSEN15 0.23 0.18 lasso 9 0.18 4.7e-21 6.9 6.8 1.2e-11 0.90 0.01 0.99 FALSE
2 GTEx Adipose Visceral Omentum RP11-181K3.4 0.13 0.06 lasso 3 0.14 8.3e-08 5.1 5.4 5.5e-08 0.04 0.04 0.95 TRUE
3 GTEx Artery Tibial LAMC1 0.10 0.10 lasso 5 0.10 2.2e-08 5.1 -5.2 1.9e-07 -0.03 0.06 0.94 FALSE
4 GTEx Artery Tibial RP11-181K3.4 0.07 0.07 lasso 15 0.05 1.1e-04 5.1 5.2 2.1e-07 0.06 0.07 0.92 FALSE
5 GTEx Brain Cerebellar Hemisphere LAMC1 0.50 0.16 enet 13 0.13 3.8e-04 5.4 5.2 1.7e-07 0.04 0.05 0.94 FALSE
6 GTEx Brain Cerebellar Hemisphere TSEN15 0.38 0.08 lasso 13 0.16 5.3e-05 6.9 6.4 1.9e-10 0.83 0.01 0.96 FALSE
7 GTEx Brain Cerebellum LAMC1 0.27 0.36 enet 29 0.29 3.5e-09 5.4 5.2 2.6e-07 0.00 0.04 0.96 FALSE
8 GTEx Esophagus Muscularis LAMC1 0.11 0.08 enet 9 0.03 4.4e-03 5.1 -5.1 2.8e-07 -0.02 0.09 0.87 FALSE
9 GTEx Esophagus Muscularis RP11-181K3.4 0.05 0.09 lasso 1 0.07 3.9e-05 5.3 5.3 1.1e-07 0.03 0.04 0.95 FALSE
10 GTEx Lung LAMC1 0.18 0.20 enet 33 0.19 2.3e-14 5.3 -5.1 3.1e-07 -0.04 0.04 0.96 FALSE
11 GTEx Nerve Tibial LAMC1 0.07 0.08 enet 30 0.05 1.1e-04 5.4 5.3 1.2e-07 0.07 0.03 0.96 FALSE
12 GTEx Nerve Tibial RP11-181K3.4 0.18 0.24 enet 30 0.24 2.9e-17 5.3 5.2 1.9e-07 0.03 0.03 0.97 FALSE
13 GTEx Thyroid RP11-181K3.4 0.12 0.07 lasso 4 0.05 5.7e-05 5.0 5.1 2.8e-07 0.05 0.06 0.93 FALSE
14 METSIM Adipose TSEN15 0.06 0.02 enet 28 0.04 1.3e-06 6.9 6.1 9.0e-10 0.76 0.01 0.99 FALSE
15 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma GLT25D2 0.05 0.01 enet 10 0.04 6.3e-05 4.8 -7.4 1.6e-13 -0.69 0.01 0.92 TRUE
16 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma GLT25D2 0.11 0.02 blup 119 0.05 5.1e-06 -1.7 -5.4 6.6e-08 -0.50 0.14 0.32 FALSE
17 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LAMC1 0.04 0.03 blup 108 0.04 1.2e-05 5.3 -5.2 2.3e-07 -0.04 0.04 0.96 FALSE
18 The Cancer Genome Atlas Brain Lower Grade Glioma TSEN15 0.11 0.08 blup 52 0.10 6.7e-12 6.9 5.7 9.7e-09 0.78 0.01 0.99 FALSE
19 The Cancer Genome Atlas Thyroid Carcinoma LAMC1 0.06 0.04 blup 109 0.05 1.3e-05 5.1 -5.1 2.7e-07 -0.07 0.04 0.96 FALSE