Best TWAS P=2.12e-12 · Best GWAS P=3.36e-13 conditioned to 0.00409
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Esophageal Carcinoma | HOXD12 | 0.21 | 0.05 | blup | 48 | 0.13 | 6.3e-05 | 6.2 | -6.9 | 5.3e-12 | -0.63 | 0.01 | 0.60 | FALSE |
| 2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | HOXD11 | 0.03 | 0.02 | enet | 7 | 0.03 | 5.8e-04 | 6.8 | -7.0 | 2.1e-12 | -0.78 | 0.01 | 0.93 | TRUE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | HOXD10 | 0.06 | 0.03 | enet | 6 | 0.03 | 5.6e-03 | -5.0 | -5.1 | 3.0e-07 | -0.67 | 0.01 | 0.70 | FALSE |