TWAS
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Traits
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Traits
:
Arm fat-free mass (left)
:
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chr2:176,716,469-177,229,392
Best TWAS P=2.12e-12 · Best GWAS P=3.36e-13 conditioned to 0.00409
176.7M
176.8M
176.9M
177M
177.1M
177.2M
0
2
4
6
8
10
12
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Head and Neck Squamous Cell Carcinoma
HOXD11
0.03
0.02
enet
7
0.03
5.8e-04
6.8
-7.0
2.1e-12
-0.78
0.01
0.93
TRUE
1
The Cancer Genome Atlas
Esophageal Carcinoma
HOXD12
0.21
0.05
blup
48
0.13
6.3e-05
6.2
-6.9
5.3e-12
-0.63
0.01
0.60
FALSE
3
The Cancer Genome Atlas
Kidney Renal Papillary Cell Carcinoma
HOXD10
0.06
0.03
enet
6
0.03
5.6e-03
-5.0
-5.1
3.0e-07
-0.67
0.01
0.70
FALSE