[Hub]/) : Traits : Arm fat-free mass (left) :

chr2:182,305,254-184,594,404

Best TWAS P=1.5e-12 · Best GWAS P=2.06e-13 conditioned to 0.00159

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial FRZB 0.14 0.04 enet 16 0.05 9.6e-05 -2.71 -5.2 2.4e-07 -0.22 0.92 0.01 FALSE
2 GTEx Brain Hypothalamus PDE1A 0.24 -0.01 enet 21 -0.01 7.6e-01 5.98 7.1 1.5e-12 0.59 0.07 0.28 TRUE
3 GTEx Liver NCKAP1 0.50 -0.01 lasso 10 0.01 1.4e-01 4.61 6.0 2.0e-09 0.11 0.05 0.08 TRUE
4 GTEx Skin Sun Exposed Lower leg PDE1A 0.11 0.07 lasso 4 0.04 6.0e-04 5.27 -5.7 1.0e-08 -0.69 0.22 0.75 FALSE
5 The Cancer Genome Atlas Breast Invasive Carcinoma PDE1A 0.03 0.01 blup 209 0.02 1.3e-05 -0.69 5.6 2.4e-08 0.35 0.45 0.08 FALSE
6 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PDE1A 0.05 0.04 blup 206 0.04 5.0e-05 -5.15 5.9 3.5e-09 0.42 0.64 0.03 FALSE