Best TWAS P=1.37e-14 · Best GWAS P=1.22e-22 conditioned to 6e-11
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | FNDC3B | 0.07 | 0.06 | enet | 8 | 0.05 | 3.2e-07 | -8.29 | 7.7 | 1.4e-14 | 0.04 | 0.97 | 0.00 | TRUE |
| 2 | GTEx | Ovary | TNFSF10 | 0.40 | 0.01 | lasso | 10 | 0.05 | 1.8e-02 | 0.74 | 5.3 | 1.3e-07 | 0.41 | 0.03 | 0.46 | FALSE |
| 3 | YFS | Blood | TNFSF10 | 0.09 | 0.04 | bslmm | 462 | 0.08 | 1.6e-24 | 6.32 | 5.9 | 4.3e-09 | 0.38 | 1.00 | 0.00 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | FNDC3B | 0.07 | 0.02 | enet | 6 | 0.02 | 3.9e-03 | 6.91 | -7.1 | 1.4e-12 | -0.83 | 0.01 | 0.98 | TRUE |