TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Arm fat-free mass (left)
:
←
→
chr4:57,127,848-58,522,810
Best TWAS P=9.62e-08 · Best GWAS P=3.7e-07 conditioned to 1
57.2M
57.4M
57.6M
57.8M
58M
58.2M
58.4M
58.6M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
METSIM
Adipose
RP11-738E22.3
0.07
0.04
lasso
6
0.05
7.7e-08
-5.1
5.3
9.6e-08
-0.98
0.00
0.99
TRUE
2
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
REST
0.04
0.01
lasso
5
0.02
7.8e-04
-5.1
-5.3
1.3e-07
0.86
0.01
0.93
FALSE