[Hub]/) : Traits : Arm fat-free mass (left) :

chr4:86,236,934-88,430,396

Best TWAS P=2e-10 · Best GWAS P=4.97e-10 conditioned to 0.0251

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PTPN13 0.13 0.18 bslmm 418 0.18 6.8e-22 5.3 -5.6 1.8e-08 -0.44 0.37 0.63 FALSE
2 GTEx Artery Aorta MAPK10 0.15 0.17 enet 16 0.17 1.4e-09 5.8 -5.8 7.7e-09 -0.81 0.02 0.98 FALSE
3 GTEx Colon Sigmoid MAPK10 0.25 0.11 lasso 8 0.07 1.6e-03 5.9 -6.4 2.0e-10 -0.74 0.02 0.95 TRUE
4 GTEx Thyroid PTPN13 0.41 0.31 lasso 6 0.30 3.2e-23 6.0 5.8 5.1e-09 0.81 0.01 0.99 FALSE
5 ROSMAP Brain Pre-frontal Cortex PTPN13 0.09 0.03 blup 409 0.07 4.7e-09 5.3 -5.4 5.8e-08 -0.45 0.35 0.65 FALSE