Best TWAS P=6.19e-09 · Best GWAS P=2.39e-11 conditioned to 0.000295
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | IBSP | 0.05 | 0.05 | lasso | 6 | 0.07 | 1.2e-13 | -6.6 | 5.7 | 1.2e-08 | -0.79 | 0.00 | 1.00 | FALSE |
| 2 | The Cancer Genome Atlas | Colon Adenocarcinoma | IBSP | 0.09 | 0.02 | enet | 15 | 0.07 | 9.4e-05 | -1.9 | 5.2 | 1.9e-07 | -0.62 | 0.02 | 0.62 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | IBSP | 0.08 | 0.00 | blup | 77 | 0.00 | 1.6e-01 | -4.4 | 5.8 | 6.2e-09 | -0.71 | 0.02 | 0.63 | TRUE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | IBSP | 0.06 | 0.01 | blup | 78 | 0.03 | 7.7e-05 | -6.6 | 5.7 | 1.1e-08 | -0.75 | 0.00 | 0.99 | FALSE |