Best TWAS P=9.16e-33 · Best GWAS P=4.76e-40 conditioned to 0.409
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | OTUD4 | 0.06 | 0.04 | bslmm | 272 | 0.04 | 2.6e-05 | -10.2 | -8.3 | 1.2e-16 | -0.39 | 0.52 | 0.40 | FALSE |
| 2 | GTEx | Brain Hypothalamus | HHIP-AS1 | 0.12 | 0.02 | enet | 16 | 0.04 | 4.6e-02 | 7.9 | 8.0 | 9.6e-16 | 0.21 | 0.06 | 0.22 | TRUE |
| 3 | GTEx | Pancreas | ANAPC10 | 0.14 | 0.10 | lasso | 3 | 0.10 | 4.3e-05 | -11.3 | 11.0 | 2.7e-28 | 0.60 | 0.32 | 0.10 | TRUE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | OTUD4 | 0.04 | 0.03 | lasso | 2 | 0.03 | 1.4e-04 | 11.7 | -11.9 | 9.2e-33 | -0.85 | 0.14 | 0.79 | TRUE |