[Hub]/) : Traits : Arm predicted mass (left) :

chr1:752,566-3,191,909

Best TWAS P=4.72e-12 · Best GWAS P=3.8e-10 conditioned to 2.93e-08

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SLC35E2 0.35 0.15 enet 24 0.17 1.0e-20 -6.2 5.7 1.6e-08 -0.71 0.01 0.99 FALSE
2 GTEx Adipose Subcutaneous C1orf86 0.15 0.05 enet 10 0.04 2.0e-04 -4.8 -6.5 9.1e-11 0.37 0.37 0.17 FALSE
3 GTEx Adipose Visceral Omentum RP1-283E3.4 0.26 0.05 enet 25 0.16 1.5e-08 -2.8 -5.4 7.6e-08 0.21 0.14 0.12 TRUE
4 GTEx Brain Cerebellar Hemisphere NADK 0.18 0.11 lasso 7 0.09 3.1e-03 -5.8 -5.9 3.6e-09 0.85 0.03 0.65 FALSE
5 GTEx Brain Cerebellar Hemisphere RP5-890O3.9 0.24 0.02 lasso 9 0.02 1.3e-01 -6.3 6.9 4.7e-12 -0.91 0.02 0.68 TRUE
6 GTEx Esophagus Gastroesophageal Junction RP11-181G12.2 0.16 0.02 enet 18 0.01 1.1e-01 4.9 5.3 1.4e-07 -0.06 0.11 0.06 TRUE
7 GTEx Esophagus Mucosa TMEM52 0.17 0.18 lasso 2 0.20 2.9e-13 -5.8 5.8 7.7e-09 -0.83 0.15 0.85 FALSE
8 GTEx Esophagus Muscularis RP11-181G12.2 0.23 0.14 lasso 4 0.19 1.0e-11 4.2 5.2 1.6e-07 -0.06 0.98 0.02 FALSE
9 GTEx Lung NADK 0.07 0.03 lasso 3 0.02 8.5e-03 5.5 -6.0 2.0e-09 0.94 0.03 0.91 FALSE
10 GTEx Muscle Skeletal NADK 0.06 0.00 enet 9 0.00 1.3e-01 -5.8 -6.1 9.7e-10 0.79 0.04 0.85 FALSE
11 GTEx Muscle Skeletal TMEM52 0.11 0.08 lasso 6 0.10 7.2e-10 -6.0 6.1 1.3e-09 -0.84 0.07 0.93 FALSE
12 GTEx Skin Not Sun Exposed Suprapubic TMEM52 0.19 0.18 lasso 4 0.14 2.6e-08 5.5 5.8 5.2e-09 -0.92 0.03 0.97 FALSE
13 GTEx Skin Sun Exposed Lower leg TMEM52 0.17 0.14 lasso 7 0.15 2.0e-12 6.1 6.2 7.1e-10 -0.92 0.02 0.98 FALSE
14 GTEx Spleen TMEM52 0.47 0.21 lasso 5 0.22 2.3e-06 -3.8 -5.3 8.9e-08 0.58 0.25 0.36 FALSE
15 METSIM Adipose TNFRSF14 0.07 0.05 blup 373 0.05 1.9e-07 4.0 6.5 6.0e-11 -0.08 0.85 0.10 TRUE
16 ROSMAP Brain Pre-frontal Cortex C1orf222 0.11 0.14 enet 18 0.14 1.8e-17 -4.4 6.0 2.6e-09 -0.70 0.98 0.02 FALSE
17 ROSMAP Brain Pre-frontal Cortex MMP23B 0.05 0.04 lasso 2 0.03 1.9e-04 -5.4 -5.4 6.0e-08 0.80 0.07 0.91 FALSE
18 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma TMEM52 0.02 0.01 blup 37 0.02 6.6e-03 -5.8 6.1 1.3e-09 -0.91 0.01 0.76 FALSE