[Hub]/) : Traits : Arm predicted mass (left) :

chr6:124,741,508-127,355,237

Best TWAS P=7.25e-33 · Best GWAS P=1.54e-33 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CENPW 0.04 0.06 lasso 10 0.06 2.4e-07 11.908 -11.9 7.2e-33 -0.99 0.02 0.98 TRUE
2 CommonMind Brain Pre-frontal Cortex HEY2 0.15 0.20 lasso 10 0.21 6.7e-25 -8.840 -8.8 1.4e-18 -0.07 0.01 0.99 FALSE
3 GTEx Artery Coronary TPD52L1 0.31 -0.01 enet 19 0.05 7.0e-03 0.095 -5.8 5.0e-09 -0.15 0.03 0.54 FALSE
4 GTEx Esophagus Muscularis HINT3 0.08 0.00 enet 14 0.00 2.9e-01 8.666 -7.3 3.1e-13 -0.11 0.07 0.04 FALSE
5 GTEx Heart Atrial Appendage CENPW 0.17 0.01 enet 15 0.06 1.8e-03 11.943 -5.9 2.9e-09 -0.70 0.03 0.53 FALSE
6 GTEx Pancreas HEY2 0.28 0.11 lasso 3 0.10 3.5e-05 -6.214 -7.0 2.1e-12 -0.05 0.10 0.90 FALSE
7 GTEx Skin Sun Exposed Lower leg HINT3 0.08 0.01 lasso 4 0.03 2.0e-03 -4.630 -5.9 3.0e-09 -0.19 0.22 0.14 FALSE
8 GTEx Testis HEY2 0.31 0.17 lasso 5 0.19 7.4e-09 -8.781 -8.8 1.3e-18 -0.07 0.01 0.99 FALSE
9 GTEx Thyroid HEY2 0.22 0.24 lasso 6 0.23 1.0e-17 -8.781 -8.9 3.5e-19 -0.08 0.01 0.99 TRUE
10 GTEx Vagina CENPW 0.24 -0.01 lasso 8 -0.01 7.9e-01 4.854 6.0 1.7e-09 0.40 0.04 0.07 FALSE
11 METSIM Adipose CENPW 0.02 0.02 blup 189 0.01 8.3e-03 11.943 -7.8 6.1e-15 -0.74 0.02 0.75 FALSE
12 METSIM Adipose HEY2 0.02 0.04 lasso 1 0.02 1.6e-04 -6.172 -6.2 6.7e-10 -0.06 0.02 0.97 FALSE
13 METSIM Adipose NCOA7 0.05 0.05 enet 5 0.05 1.9e-07 6.691 8.6 6.8e-18 0.23 0.95 0.02 FALSE
14 ROSMAP Brain Pre-frontal Cortex HEY2 0.10 0.12 enet 15 0.13 9.8e-17 8.382 -8.0 1.2e-15 -0.06 0.02 0.98 FALSE
15 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CENPW 0.04 0.05 lasso 5 0.05 2.6e-06 11.980 -11.5 8.8e-31 -0.98 0.02 0.98 FALSE
16 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma HEY2 0.05 0.05 blup 36 0.05 4.9e-06 -6.214 -5.2 2.2e-07 -0.04 0.18 0.82 FALSE
17 The Cancer Genome Atlas Brain Lower Grade Glioma CENPW 0.04 0.06 blup 35 0.05 9.2e-07 11.835 -11.7 1.3e-31 -0.98 0.02 0.98 FALSE
18 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma HEY2 0.09 0.06 lasso 8 0.06 2.3e-03 -6.214 -6.2 7.7e-10 -0.04 0.03 0.75 FALSE
19 The Cancer Genome Atlas Thyroid Carcinoma HEY2 0.03 0.04 lasso 3 0.02 3.8e-03 7.749 -8.0 1.3e-15 -0.07 0.01 0.98 FALSE