[Hub]/) : Traits : Arm predicted mass (left) :

chr7:2,032,803-3,581,391

Best TWAS P=4.82e-28 · Best GWAS P=7.05e-27 conditioned to 0.0541

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex AMZ1 0.19 0.12 enet 22 0.13 5.7e-16 5.5 6.9 5.9e-12 -0.43 1.00 0.00 FALSE
2 GTEx Adipose Subcutaneous GNA12 0.11 0.08 lasso 4 0.07 1.3e-06 -6.3 -7.0 2.3e-12 0.76 0.10 0.90 FALSE
3 GTEx Artery Tibial GNA12 0.24 0.13 enet 20 0.22 3.5e-17 -10.6 -9.0 2.1e-19 0.84 0.02 0.98 FALSE
4 GTEx Cells EBV-transformed lymphocytes GNA12 0.46 0.51 lasso 5 0.50 7.9e-19 -10.7 -10.7 1.5e-26 0.99 0.00 1.00 FALSE
5 GTEx Cells Transformed fibroblasts GNA12 0.21 0.11 lasso 11 0.15 1.7e-11 -10.6 -8.5 2.5e-17 0.86 0.02 0.98 FALSE
6 GTEx Colon Sigmoid GNA12 0.14 0.05 lasso 3 0.03 3.6e-02 -6.3 -8.8 2.2e-18 0.87 0.02 0.92 FALSE
7 GTEx Colon Transverse GNA12 0.19 0.08 lasso 4 0.10 2.3e-05 5.2 -5.9 3.2e-09 0.58 0.33 0.64 FALSE
8 GTEx Esophagus Gastroesophageal Junction GNA12 0.20 0.12 lasso 6 0.12 3.4e-05 -6.3 -8.7 3.6e-18 0.86 0.04 0.95 FALSE
9 GTEx Esophagus Mucosa GNA12 0.16 0.13 lasso 3 0.13 3.0e-09 -10.4 -9.5 2.0e-21 0.87 0.02 0.98 FALSE
10 GTEx Esophagus Muscularis GNA12 0.32 0.31 lasso 3 0.34 2.1e-21 -10.6 -10.2 1.8e-24 0.94 0.01 0.99 FALSE
11 GTEx Lung GNA12 0.16 0.08 enet 21 0.12 1.2e-09 -10.3 -8.2 2.4e-16 0.78 0.01 0.99 FALSE
12 GTEx Nerve Tibial GNA12 0.31 0.34 lasso 7 0.36 9.6e-27 -6.4 -8.5 2.0e-17 0.86 0.74 0.26 FALSE
13 GTEx Skin Not Sun Exposed Suprapubic GNA12 0.10 0.15 lasso 3 0.12 4.2e-07 4.7 -5.2 1.6e-07 0.54 0.30 0.69 FALSE
14 GTEx Skin Sun Exposed Lower leg GNA12 0.17 0.16 lasso 3 0.18 1.3e-14 -6.2 -8.4 4.0e-17 0.87 0.12 0.88 FALSE
15 GTEx Small Intestine Terminal Ileum GNA12 0.34 0.20 lasso 5 0.16 2.4e-04 -6.3 -6.9 4.7e-12 0.72 0.05 0.83 FALSE
16 GTEx Stomach GNA12 0.18 0.16 lasso 2 0.13 6.6e-07 -6.3 -6.3 2.4e-10 0.70 0.25 0.74 FALSE
17 GTEx Whole Blood GNA12 0.09 0.01 enet 4 0.00 3.3e-01 -10.3 -10.4 3.7e-25 0.94 0.02 0.92 FALSE
18 METSIM Adipose GNA12 0.07 0.05 lasso 3 0.05 3.3e-08 -6.3 -6.4 1.7e-10 0.72 0.25 0.75 FALSE
19 NTR Blood GNA12 0.07 0.03 bslmm 597 0.06 1.3e-17 -7.6 -7.7 2.0e-14 0.63 0.89 0.11 FALSE
20 ROSMAP Brain Pre-frontal Cortex AMZ1 0.09 0.05 lasso 6 0.04 2.4e-06 -10.6 11.0 4.8e-28 -0.90 0.01 0.99 TRUE
21 YFS Blood GNA12 0.23 0.15 bslmm 570 0.25 4.5e-82 5.5 -7.2 8.0e-13 0.52 1.00 0.00 FALSE
22 The Cancer Genome Atlas Esophageal Carcinoma AMZ1 0.18 0.05 blup 69 0.05 1.4e-02 6.8 -9.4 5.1e-21 0.71 0.01 0.70 FALSE
23 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma GNA12 0.03 0.04 lasso 1 0.04 3.0e-05 -6.3 -6.3 3.3e-10 0.72 0.07 0.78 FALSE
24 The Cancer Genome Atlas Brain Lower Grade Glioma AMZ1 0.04 0.04 lasso 3 0.02 1.3e-03 6.8 7.8 4.5e-15 -0.60 0.03 0.91 FALSE
25 The Cancer Genome Atlas Lung Adenocarcinoma GNA12 0.03 0.01 enet 7 0.02 1.5e-03 4.1 -8.6 7.8e-18 0.78 0.06 0.74 FALSE