[Hub]/) : Traits : Arm predicted mass (left) :

chr9:97,520,168-100,366,953

Best TWAS P=6.2e-15 · Best GWAS P=1.83e-19 conditioned to 1.02e-12

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex LOC441454 0.05 0.01 lasso 3 0.02 1.5e-03 4.9 5.5 4.1e-08 0.05 0.04 0.55 FALSE
2 GTEx Artery Tibial RP11-435O5.5 0.09 0.04 lasso 2 0.02 7.3e-03 8.0 -7.8 6.2e-15 0.18 0.22 0.15 TRUE
3 GTEx Breast Mammary Tissue CDC14B 0.16 0.02 enet 21 0.02 3.7e-02 6.5 -5.4 7.4e-08 -0.01 0.07 0.86 FALSE
4 GTEx Cells EBV-transformed lymphocytes AAED1 0.17 0.02 lasso 3 0.04 2.4e-02 6.5 5.8 6.1e-09 0.00 0.05 0.47 FALSE
5 GTEx Liver PTCH1 0.25 0.06 enet 11 0.03 4.9e-02 8.1 5.2 1.9e-07 -0.11 0.16 0.07 FALSE
6 GTEx Nerve Tibial ZNF367 0.10 0.05 lasso 3 0.02 7.9e-03 6.8 6.1 1.1e-09 -0.01 0.04 0.95 FALSE
7 GTEx Testis HABP4 0.19 0.22 lasso 9 0.21 1.1e-09 6.6 6.6 4.4e-11 -0.02 0.06 0.94 FALSE
8 GTEx Thyroid CDC14B 0.15 0.10 lasso 5 0.08 5.3e-07 6.1 -6.3 3.7e-10 -0.03 0.22 0.77 FALSE
9 NTR Blood PTCH1 0.04 0.02 blup 433 0.02 4.1e-08 5.9 5.2 1.5e-07 -0.08 0.92 0.07 TRUE
10 YFS Blood HABP4 0.08 0.09 enet 24 0.11 5.9e-34 6.7 -6.4 1.7e-10 0.03 0.03 0.97 FALSE
11 YFS Blood PTCH1 0.09 0.05 lasso 8 0.05 1.2e-15 5.8 6.8 1.0e-11 -0.10 0.31 0.69 FALSE
12 The Cancer Genome Atlas Breast Invasive Carcinoma CDC14B 0.02 0.01 lasso 1 0.01 3.0e-03 6.7 -6.7 1.6e-11 0.02 0.03 0.56 FALSE
13 The Cancer Genome Atlas Glioblastoma Multiforme CDC14B 0.16 0.17 blup 41 0.19 2.6e-06 6.5 -5.9 3.2e-09 0.02 0.05 0.92 FALSE
14 The Cancer Genome Atlas Glioblastoma Multiforme HABP4 0.08 0.06 blup 44 0.05 1.6e-02 6.0 -6.8 1.1e-11 0.02 0.03 0.49 FALSE
15 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma HABP4 0.02 0.02 blup 44 0.02 7.1e-03 6.5 6.7 1.9e-11 -0.03 0.03 0.65 FALSE
16 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CDC14B 0.03 0.02 blup 42 0.02 2.1e-03 6.5 -6.7 2.8e-11 0.02 0.04 0.63 FALSE
17 The Cancer Genome Atlas Brain Lower Grade Glioma CDC14B 0.05 0.06 lasso 5 0.06 6.5e-07 6.5 -6.1 9.5e-10 0.01 0.07 0.93 FALSE
18 The Cancer Genome Atlas Brain Lower Grade Glioma HABP4 0.05 0.08 lasso 5 0.08 6.9e-09 5.9 -6.2 7.5e-10 0.01 0.11 0.89 FALSE
19 The Cancer Genome Atlas Prostate Adenocarcinoma PTCH1 0.02 0.01 blup 54 0.02 1.1e-03 6.8 -6.6 5.6e-11 0.27 0.06 0.07 FALSE
20 The Cancer Genome Atlas Stomach Adenocarcinoma CDC14B 0.08 0.02 blup 41 0.04 1.0e-03 4.9 -7.0 2.4e-12 0.03 0.02 0.59 TRUE
21 The Cancer Genome Atlas Thyroid Carcinoma CDC14B 0.05 0.07 blup 42 0.08 4.8e-08 6.5 -6.5 7.3e-11 0.03 0.06 0.94 FALSE