TWAS hub - LOC441454

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0460	0.0270	0.0110	0.010	0.004	0.001	0.003	0.020	0.0190	0.1100	0.240	0.14	0.0015
2	TCGA	Brain Lower Grade Glioma	0.0315	0.0383	0.0075	0.023	0.014	0.011	NA	0.018	0.0011	0.0087	0.017	NA	0.0031

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Height	6.6	126.5	252.8	15.9	-0.5
Sitting height	6.2	44.1	86.9	9.3	-1.1
Standing height	5.4	53.1	106.1	10.3	-0.4
Blood Platelet Count	5.3	61.5	118.8	-10.9	-2.1
High blood pressure (mother)	4.8	6.7	8.0	-2.8	-2.3
Trunk fat-free mass	4.7	26.9	53.9	7.3	-0.1
Trunk predicted mass	4.7	27.0	54.0	7.3	-0.1
Intelligence (Savage-Jansen 2018)	4.6	14.0	28.1	5.3	0.1
Verbal and Numeric Reasoning (VNR)	4.0	9.7	19.3	4.4	-0.2
Whole body water mass	4.0	22.8	45.3	6.7	-0.6
Whole body fat-free mass	3.9	22.5	44.6	6.7	-0.6
Arm fat-free mass (right)	3.8	19.6	38.5	6.2	-0.8
Arm predicted mass (right)	3.8	19.5	38.3	6.2	-0.9
Basal metabolic rate	3.6	19.8	38.8	6.2	-0.9
Comparative height size at age 10	3.2	17.7	33.6	5.8	-1.3
Type 2 Diabetes (T2D) (2012)	3.1	3.6	7.2	-2.7	0.0
Leg fat-free mass (left)	3.1	16.2	30.5	5.5	-1.4
Fluid intelligence score	3.1	6.5	13.0	3.6	0.1
Leg predicted mass (left)	3.0	15.7	29.5	5.4	-1.4
Arm fat-free mass (left)	3.0	15.3	30.4	5.5	-0.4
Arm predicted mass (left)	3.0	15.2	30.0	5.5	-0.7
Leg fat-free mass (right)	2.9	15.4	29.6	5.4	-1.1
Chronotype (morning person)	2.8	6.4	12.7	-3.6	-0.4
Forced expiratory volume in 1-second (FEV1), predicted	2.8	5.7	5.9	2.4	2.3
Leg predicted mass (right)	2.8	14.7	28.2	5.3	-1.1
Alcohol usually taken with meals	2.7	4.4	4.6	-2.1	2.0
Qualifications: CSEs or equivalent	2.6	3.4	3.5	-1.8	1.9
Age at First Birth	2.5	3.6	5.1	2.3	1.5
Medication: Co-codamol	2.4	2.8	4.5	1.1	2.1
Ever smoked	2.4	4.2	7.9	-2.8	0.8
HbA1C	2.3	2.5	4.5	-2.1	0.8
Diverticular disease/diverticulitis (self-reported)	2.3	2.7	2.9	1.7	1.6
Forced vital capacity (FVC)	2.3	8.9	17.7	4.2	-0.4
Father’s age at death	2.3	3.1	3.4	1.7	1.8
Number of children fathered	2.3	2.6	4.5	-0.8	-2.1
Weight	2.2	10.9	18.1	4.3	-1.9
Commuting to job workplace: Cycle	2.2	2.7	4.2	1.1	2.0
Hayfever/allergic rhinitis (self-reported)	2.1	2.8	5.4	2.3	0.5
Serious illness, injury or assault of a close relative in last 2 years	2.1	2.4	2.4	1.6	1.6
Forced vital capacity (FVC), Best measure	2.1	7.8	15.2	3.9	-0.6
Medication for pain relief, constipation, heartburn	2.1	3.6	4.2	-1.7	2.1
Medication: Seretide 50 evohaler	2.1	2.4	2.5	1.5	-1.6
Number of operations (self-reported)	2.1	3.1	4.9	2.2	-1.2
Heart attack/myocardial infarction (self-reported)	2.1	2.8	5.3	0.4	-2.3
Illnesses of siblings	2.0	2.9	3.5	1.5	1.9
Pulse wave peak to peak time	2.0	2.4	2.7	1.4	-1.6
Commuting to job workplace: Public transport	2.0	2.4	4.6	2.1	0.5
Heart attack	1.9	2.4	4.4	0.6	-2.1
Noisy workplace	1.9	2.3	4.1	-0.7	-2.0
Seen a psychiatrist for nerves, anxiety, tension or depression	1.9	2.4	4.7	2.2	0.3
Osteoporosis (self-reported)	1.9	2.3	4.3	0.5	2.1
Alzheimer’s Disease (in mother)	1.8	2.1	2.6	1.6	1.3
Prospective memory result	1.8	2.2	3.8	-0.8	2.0
Chronic bronchitis/emphysema (mother)	1.8	2.1	2.8	1.2	1.7
Forced expiratory volume in 1-second (FEV1)	1.7	5.8	11.4	3.4	-0.5
Medication: Aspirin	1.7	2.3	2.5	1.4	-1.6
Eye problems/disorders: Cataract	1.7	2.0	2.0	1.4	1.4
Ever taken oral contraceptive pill	1.7	1.9	3.5	-0.5	1.9
Body Mass Index (BMI) (2010)	1.6	2.2	4.0	0.5	2.0
Birth weight of first child	1.6	2.9	3.0	1.7	1.7
Medication: Blood pressure	1.6	2.8	5.7	2.4	-0.1
Chest pain or discomfort	1.6	2.3	2.3	1.5	-1.5
Long-standing illness, disability or infirmity	1.6	2.4	4.0	2.0	-0.9
Ever had prostate specific antigen (PSA) test	1.6	1.9	2.2	1.5	1.2
Hip circumference	1.5	6.3	8.5	2.9	-2.0
Falls in the last year	1.5	2.1	3.7	-1.9	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	1.5	4.8	9.0	3.0	-0.8
High blood pressure (siblings)	1.5	2.2	3.0	-1.7	-1.2
Medication: Aspirin	1.5	1.9	2.0	1.4	-1.4
Supplements: Glucosamine	1.4	1.8	2.3	-1.5	-1.1
Frequency of tenseness / restlessness in last 2 weeks	1.4	2.1	3.6	-1.9	-0.8
Hair/balding pattern: Pattern 2	1.4	1.8	3.3	0.5	-1.8
Ever unenthusiastic/disinterested for a whole week	1.4	1.7	3.3	-0.0	1.8
Pulse wave Arterial Stiffness index	1.4	1.6	2.5	-0.8	1.6
Medication: Ventolin 100micrograms inhaler	1.4	1.8	3.5	-0.1	-1.9
Alcohol drinker status: Never	1.4	1.7	2.2	1.1	-1.5
Medication: Atenolol	1.3	1.6	2.8	1.7	0.6
Nervous feelings	1.3	2.4	2.6	1.5	-1.6
Happiness	1.3	1.5	2.2	0.9	1.5
Wheeze or whistling in the chest in last year	1.3	2.3	4.0	-2.0	-0.8
Had major operations	1.3	1.6	2.8	0.6	-1.7
Commuting to job workplace: Car/motor vehicle	1.3	1.5	3.0	-1.7	-0.0
Commuting to job workplace: Walk	1.3	1.4	1.5	1.2	-1.1
Breast cancer (self-reported)	1.3	1.5	2.9	1.7	0.4
Breast Cancer	1.2	2.8	5.4	-2.3	-0.5
LDL Cholesterol	1.2	1.9	3.0	1.7	0.9
Heel bone mineral density (BMD) T-score, automated (left)	1.2	2.8	5.5	-2.3	-0.4
Heel bone mineral density (BMD) T-score, automated (right)	1.2	2.7	3.8	-1.9	1.3
Neuroticism score	1.2	2.5	4.6	2.2	-0.6
Worrier / anxious feelings	1.2	2.3	3.9	2.0	-0.8
Medication: Ibuprofen (e.g. Nurofen)	1.2	1.5	2.2	1.5	-0.9
Mouth/teeth dental problems: Bleeding gums	1.2	1.5	2.0	1.0	-1.4
Qualifications: College or University degree	1.2	3.8	3.9	1.9	2.0
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.4	2.5	-1.6	-0.6
Qualifications: nursing, teaching	1.2	1.9	3.0	0.9	1.7
Guilty feelings	1.2	1.8	2.5	1.0	-1.6
Impedance of leg (left)	1.1	5.3	9.4	-3.1	1.1
Illnesses of mother	1.1	1.4	2.3	1.5	0.6
Peak expiratory flow (PEF)	1.1	2.6	4.0	2.0	-1.0
Exposure to tobacco smoke outside home	1.1	1.4	2.8	0.0	-1.7
Family relationship satisfaction	1.1	1.4	2.4	0.6	1.6
Average weekly red wine intake	1.1	1.6	2.8	1.7	0.7
Mother’s age at death	1.1	1.3	2.6	-1.6	0.2
Reaction Time	1.0	1.8	2.7	-1.7	1.0
Bipolar Disorder (2011)	1.0	1.0	2.0	-1.4	0.0
Smoking Status	1.0	2.4	4.9	-2.2	-0.0
Vitamin and mineral supplements	1.0	1.3	1.9	1.4	0.8
Hand grip strength (right)	1.0	2.8	3.3	1.8	-1.5
Fed-up feelings	1.0	1.8	3.5	1.9	-0.1
Taking other prescription medications	1.0	1.5	2.1	1.0	-1.4
Tinnitus: Yes, but not now, but have in the past	1.0	1.1	1.8	-1.3	-0.6
High blood pressure	1.0	2.9	5.8	2.4	-0.3
Had menopause	1.0	1.2	2.2	0.5	-1.5
Number of live births	1.0	1.4	1.9	-1.4	1.0
Asthma	1.0	1.9	2.1	1.4	-1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.6	2.4	1.6	0.9
Pulse wave reflection index	1.0	1.3	1.7	-0.9	1.3
Heart disease (mother)	1.0	1.3	1.4	-1.2	-1.1
Age at last live birth	1.0	1.5	3.0	0.1	1.7
Alcohol drinker status: Previous	1.0	1.1	1.4	-0.9	-1.2
Worry (Nagel 2018)	0.9	1.9	2.9	0.9	-1.7
Neuroticism	0.9	2.1	4.0	2.0	-0.4
Other serious medical condition/disability diagnosed by doctor	0.9	1.1	2.2	1.5	0.3
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	1.5	-1.2	0.7
Trunk fat mass	0.9	3.9	4.9	1.7	-2.2
Past tobacco smoking	0.9	1.6	2.4	1.6	-0.8
Diabetes (self-reported)	0.9	1.4	1.5	-1.2	-1.1
Medication: Simvastatin	0.9	1.3	2.1	-1.4	0.7
Qualifications: A levels/AS levels or equivalent	0.9	1.9	2.7	1.1	1.6
Worry too long after embarrassment	0.9	1.5	2.9	1.7	-0.3
Medication: Allopurinol	0.9	1.2	1.9	-0.7	-1.4
Supplements: Vitamin C	0.9	1.1	1.2	-1.0	-1.1
Medication: Atorvastatin	0.9	1.1	2.3	1.5	-0.1
Impedance of whole body	0.9	4.5	9.0	-3.0	0.1
Mean Putamen Volume	0.8	0.9	1.7	-1.3	0.0
Medication for hormone replacement therapy	0.8	0.9	1.8	0.0	-1.3
Diabetes (mother)	0.8	1.0	1.7	-0.6	-1.3
Age when periods started (menarche)	0.8	1.9	3.8	0.0	1.9
Medication: Cholesterol lowering	0.8	1.2	2.2	-1.5	-0.5
Gout (self-reported)	0.8	1.1	1.5	-1.2	-0.9
Whole body fat mass	0.8	3.2	4.8	1.3	-2.2
Number of full sisters	0.8	1.0	1.6	-0.7	-1.3
Suffer from ‘nerves’	0.8	1.2	2.4	1.5	-0.2
Asthma (self-reported)	0.8	1.6	2.0	1.1	-1.4
Number of self-reported non-cancer illnesses	0.8	1.4	2.6	1.6	-0.6
Financial situation satisfaction	0.8	1.1	1.3	-0.9	1.1
Eye problems/disorders: Glaucoma	0.8	0.9	1.3	-1.1	-0.8
Bipolar Disorder or Schizophrenia	0.7	1.7	3.3	-1.8	0.0
Ulcerative Colitis (UC)	0.7	1.3	2.5	-0.3	-1.6
Primary Biliary Cirrhosis	0.7	1.0	1.9	-1.4	0.3
Number of treatments/medications taken	0.7	1.2	2.3	0.4	-1.5
Ever used hormone-replacement therapy (HRT)	0.7	0.9	1.7	1.3	-0.2
Impedance of leg (right)	0.7	3.3	6.2	-2.5	0.6
Trunk fat percentage	0.7	2.6	5.1	-0.5	-2.2
Maternal smoking around birth	0.7	1.0	1.0	1.0	-1.0
Multivitamins +/- minerals	0.7	0.9	1.5	-1.2	0.5
Medication: Ramipril	0.7	0.9	1.0	-0.9	-1.0
Impedance of arm (right)	0.7	3.3	6.5	-2.5	-0.3
Hair/balding pattern: Pattern 3	0.7	1.0	1.9	-1.4	-0.4
Mouth/teeth dental problems: Dentures	0.7	1.1	2.0	-1.4	0.5
Loud music exposure frequency	0.7	0.8	0.9	-0.8	1.0
Blood clot in the leg (DVT)	0.7	0.9	1.0	-0.9	-1.0
Body fat percentage	0.7	2.9	5.2	-0.8	-2.3
Leg fat percentage (right)	0.7	2.6	4.5	-0.9	-2.1
Health satisfaction	0.7	0.9	1.5	0.5	1.2
Eye problems/disorders: None of the above	0.7	0.8	1.2	-1.1	-0.7
Migraine (self-reported)	0.7	0.9	1.1	0.8	-1.0
Medication: Ibuprofen	0.7	0.8	1.0	1.0	-0.8
Leg fat mass (right)	0.7	2.9	4.6	1.1	-2.1
Hypertension (Self-reported)	0.7	2.1	4.0	2.0	-0.3
Smoking status: Previous	0.7	1.0	1.8	-0.5	1.3
Arm fat percentage (left)	0.7	2.7	5.0	-0.6	-2.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.4	2.5	1.6	-0.5
Arm fat mass (left)	0.7	2.7	3.3	1.5	-1.8
Miserableness	0.7	1.3	2.5	1.6	-0.2
Hearing aid user	0.7	0.8	1.6	1.3	0.1
Vascular/heart problems diagnosed by doctor	0.7	2.0	3.4	-1.8	0.7
Bipolar Disorder (2018)	0.6	1.0	2.0	-1.4	0.0
Alzheimer’s Disease (including proxy)	0.6	0.9	1.4	1.2	0.6
Ovarian Cancer	0.6	0.8	1.6	-1.2	0.0
Type 2 Diabetes (T2D) (2018)	0.6	1.1	1.5	-0.9	-1.2
Frequency of depressed mood in last 2 weeks	0.6	0.9	1.3	0.7	-1.1
Ever had hysterectomy (womb removed)	0.6	0.7	1.0	-1.0	-0.5
Relative age voice broke	0.6	0.9	1.6	-1.3	0.4
Stomach or abdominal pain in last month	0.6	0.7	0.9	1.0	0.7
Chronic bronchitis/emphysema (father)	0.6	0.7	0.8	0.9	0.8
Waist circumference	0.6	2.1	2.9	1.7	-1.1
Arm fat percentage (right)	0.6	2.4	3.8	-1.0	-2.0
Arm fat mass (right)	0.6	2.5	4.0	1.0	-2.0
Medication: Amlodipine	0.6	0.8	1.6	1.2	-0.1
Alcohol intake frequency.	0.6	1.4	2.2	-0.8	-1.5
Mood swings	0.6	1.1	2.0	1.4	0.4
Osteoarthritis (self-reported)	0.6	0.8	1.5	1.2	-0.4
Smoking status: Current	0.6	1.0	1.1	-1.1	-0.9
Supplements: Fish oil (including cod liver oil)	0.6	0.8	1.4	-1.2	0.4
Leg fat percentage (left)	0.6	2.3	3.1	-1.3	-1.8
Basal cell carcinoma (self-reported)	0.6	0.7	1.2	-0.4	1.1
Leg fat mass (left)	0.6	2.2	3.8	0.8	-1.9
Neuroticism (Nagel 2018)	0.5	1.2	2.0	1.4	-0.7
Fasting Glucose	0.5	0.6	1.1	1.1	-0.1
Hand grip strength (left)	0.5	1.3	2.0	1.4	-0.7
Diabetes (father)	0.5	0.7	1.3	-0.1	-1.1
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	0.7	0.7	-0.8
Financial difficulties in last 2 years	0.5	0.7	1.3	0.3	1.2
Breastfed as a baby	0.5	0.6	1.1	1.1	-0.1
Ever highly irritable/argumentative for 2 days	0.5	0.6	0.9	0.5	-0.9
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	1.3	-0.6	1.1
Medication: Paracetamol	0.5	0.9	1.8	-0.1	-1.3
Birth weight	0.5	1.1	1.6	1.2	0.9
Comparative body size at age 10	0.5	1.4	2.4	-0.7	-1.5
Number of full brothers	0.5	0.6	0.7	-0.8	-0.8
Shortness of breath walking on level ground	0.5	0.5	0.6	-0.7	0.8
Emphysema/chronic bronchitis	0.5	0.5	0.7	-0.6	-0.8
Leg pain on walking	0.5	0.6	1.2	-0.2	-1.1
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.2	1.1	-0.0
Handedness (chirality/laterality): Left-handed	0.5	0.6	0.9	-0.9	0.6
Ever had bowel cancer screening	0.5	0.5	1.0	1.0	-0.2
Friendships satisfaction	0.5	0.7	0.8	0.9	0.8
Medication: Gliclazide	0.5	0.6	0.7	-0.8	0.7
Risk taking	0.5	0.8	0.8	-0.9	-0.8
Deep venous thrombosis (DVT) (self-reported)	0.5	0.7	0.9	-0.7	-1.0
Heart disease (siblings)	0.5	0.6	0.8	-0.9	-0.7
Depression (Nagel 2018)	0.4	0.7	1.3	-0.3	-1.1
Schizophrenia (2018)	0.4	0.7	1.5	-1.2	0.0
Schizophrenia (2014)	0.4	0.9	1.9	-1.4	0.0
BMI	0.4	2.4	3.5	-1.9	-1.1
Systolic Blood Pressure	0.4	2.2	3.3	1.8	1.0
Respiratory disease	0.4	1.0	1.3	1.2	0.8
Relative age of first facial hair	0.4	0.9	1.4	-1.2	0.6
Current tobacco smoking	0.4	0.7	1.0	-1.0	-0.6
Had other major operations	0.4	0.5	1.0	1.0	0.1
Impedance of arm (left)	0.4	2.0	3.7	-1.9	-0.6
Hair/balding pattern: Pattern 4	0.4	1.0	1.7	0.6	1.3
Headache pain in last month	0.4	0.7	1.3	1.1	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.4	0.8	-0.0	0.9
Mouth/teeth dental problems: Loose teeth	0.4	0.5	0.9	-0.0	-1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	0.8	-0.5	0.9
Knee pain experienced in last month	0.4	0.6	0.8	0.7	-0.9
Diabetes diagnosed by doctor	0.4	0.6	1.0	-0.5	-1.0
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	0.7	0.3	0.8
Medication for cholesterol	0.4	0.6	1.0	0.4	1.0
Medication: Blood pressure	0.4	0.7	1.4	0.3	-1.2
High cholesterol (Self-reported)	0.4	0.7	1.3	-1.2	0.0
Medication: Paracetamol	0.4	0.6	1.1	-0.2	-1.1
Medication: Lisinopril	0.4	0.5	0.7	-0.8	-0.6
Average weekly beer plus cider intake	0.4	0.6	0.8	0.9	0.5
Fractured/broken bones in last 5 years	0.4	0.5	1.0	0.2	1.0
Cholesterol lowering medication	0.4	0.5	0.9	-0.9	0.4
Depressed Affect (Nagel 2018)	0.3	0.6	1.2	1.1	0.3
Coronary Artery Disease (CAD)	0.3	0.4	0.7	0.8	0.0
HDL Cholesterol	0.3	0.5	1.0	0.0	1.0
Rheumatoid Arthritis	0.3	0.4	0.8	0.9	0.0
Blood White Count	0.3	1.9	3.4	-1.8	-0.7
Heel T-Score	0.3	2.5	4.8	-0.4	2.2
Waist Hip Ratio (WHR)	0.3	1.5	2.9	0.4	1.7
Hypothyroidism (self reported)	0.3	0.7	1.3	-0.1	1.2
Hearing difficulty/problems: Yes	0.3	0.5	1.0	0.3	-1.0
Supplements: Zinc	0.3	0.3	0.6	0.8	0.3
Severe depression (siblings)	0.3	0.3	0.7	0.1	0.8
Average weekly fortified wine intake	0.3	0.4	0.7	0.2	-0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.5	0.6	-0.6	-0.7
Body mass index (BMI)	0.3	1.2	2.4	-0.3	-1.5
Qualifications: None of the above	0.3	0.6	1.2	-0.3	-1.1
Allergy	0.3	0.6	1.0	0.4	1.0
Medication: Lansoprazole	0.3	0.3	0.5	0.3	-0.7
Length of working week for main job	0.3	0.3	0.6	-0.1	-0.8
Pulse rate, automated reading	0.3	1.0	1.6	-1.2	0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	0.7	-0.9	0.1
Illnesses of father: High blood pressure	0.3	0.4	0.4	-0.6	-0.6
Age started oral contraceptive pill	0.3	0.4	0.8	-0.2	0.9
Unable to work because of sickness or disability	0.3	0.4	0.8	-0.9	0.2
Alzheimer’s Disease (in father)	0.2	0.3	0.5	0.0	-0.7
Irritable Bowel Disease (IBD)	0.2	0.6	0.9	-0.5	-1.0
Crohns Disease (2012)	0.2	0.3	0.6	-0.8	0.0
Triglycerides	0.2	0.4	0.5	-0.7	-0.5
Average weekly spirits intake	0.2	0.3	0.5	-0.7	-0.3
Sensitivity / hurt feelings	0.2	0.3	0.6	-0.8	-0.2
Pack years adult smoking proportion	0.2	0.3	0.5	-0.4	-0.7
Serious illness, injury or assault to yourself	0.2	0.3	0.3	-0.5	-0.6
Medication: Levothyroxine sodium	0.2	0.3	0.5	-0.3	0.7
Number of incorrect matches in round	0.2	0.3	0.6	-0.8	0.1
Pain all over the body in last month	0.2	0.2	0.3	0.6	0.4
Alcohol intake versus 10 years previously	0.2	0.3	0.3	-0.6	0.6
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	0.6	-0.8	-0.1
Glaucoma (self-reported)	0.2	0.3	0.5	-0.7	-0.3
Age at first live birth	0.2	0.4	0.7	-0.3	0.8
Neck or shoulder pain in last month	0.2	0.3	0.5	0.3	-0.7
Medication: Omeprazole	0.2	0.3	0.5	-0.7	-0.2
Illnesses of father: Heart disease	0.2	0.2	0.4	-0.2	0.7
Mineral and other dietary supplements	0.2	0.2	0.3	0.5	-0.4
Average weekly champagne plus white wine intake	0.2	0.3	0.5	-0.3	0.7
Wears glasses or contact lenses	0.2	0.2	0.3	-0.3	0.6
Tinnitus: Yes, now most or all of the time	0.2	0.3	0.5	0.7	0.2
Pain type(s) experienced in last month: Hip pain	0.2	0.3	0.5	0.7	0.3
Irritability	0.2	0.4	0.8	0.9	-0.0
Diastolic blood pressure, automated reading	0.2	0.5	0.9	0.3	0.9
Pain experienced in last month	0.2	0.3	0.6	-0.8	-0.1
Pack years of smoking	0.2	0.3	0.6	-0.0	-0.8
Schizophrenia vs Biploar Disorder	0.1	0.1	0.3	0.5	0.0
Crohns Disease (2017)	0.1	0.3	0.6	-0.8	-0.0
Lupus	0.1	0.1	0.2	0.5	0.0
Neuroticism (2016)	0.1	0.1	0.1	-0.4	0.0
Blood Eosinophil Count	0.1	0.8	1.6	-1.3	-0.1
Lung FEV1/FVC ratio	0.1	0.4	0.9	-0.9	0.2
Lung FVC	0.1	0.4	0.8	0.2	-0.9
Hair Pigment	0.1	1.6	1.6	-1.3	-1.2
Systolic blood pressure, automated reading	0.1	0.2	0.4	0.6	0.1
Medication: Metformin	0.1	0.1	0.2	0.4	-0.1
Hayfever, allergic rhinitis or eczema	0.1	0.3	0.5	-0.7	-0.4
Time employed in main current job	0.1	0.1	0.1	0.4	0.3
Pulse rate	0.1	0.2	0.3	-0.5	-0.5
Depression (self-reported)	0.1	0.1	0.2	-0.0	-0.5
Lung cancer (father)	0.1	0.1	0.3	0.5	-0.2
Exposure to tobacco smoke at home	0.1	0.1	0.3	-0.0	-0.5
Tense / ‘highly strung’	0.1	0.1	0.3	0.5	-0.2
Mean time to correctly identify matches	0.1	0.2	0.3	-0.5	0.4
Overall health rating	0.1	0.3	0.6	-0.1	-0.7
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.4	0.6	-0.3
Back pain experienced in last month	0.1	0.2	0.2	0.3	0.5
Medication: Bendroflumethiazide	0.1	0.2	0.4	0.1	0.6
Medication: Omeprazole (e.g. Zanprol)	0.1	0.2	0.2	-0.5	-0.3
Major Depression (MDD)	0.0	0.0	0.0	-0.1	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.0	0.0	0.0	-0.1	0.0
Blood Red Count	0.0	0.4	0.7	0.8	-0.3
Allergy or Eczema	0.0	0.0	0.0	-0.2	0.1
Cardiovascular Disease	0.0	0.0	0.1	0.1	-0.3
Tanning	0.0	0.5	0.9	0.4	-0.9
Angina	0.0	0.0	0.0	0.1	-0.2
Townsend deprivation index at recruitment	0.0	0.0	0.0	0.0	-0.2
Hearing difficulty/problems with background noise	0.0	0.0	0.0	0.0	-0.1
Mouth/teeth dental problems	0.0	0.0	0.0	-0.2	0.0
Frequency of tiredness / lethargy in last 2 weeks	0.0	0.0	0.0	-0.1	0.0
Hypothyroidism/myxoedema (self-reported)	0.0	0.1	0.2	-0.2	0.4
Angina (self-reported)	0.0	0.0	0.0	0.1	-0.1
Illnesses of siblings: Diabetes	0.0	0.1	0.1	-0.0	-0.3
Loneliness, isolation	0.0	0.0	0.1	-0.1	0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.0	0.0	0.1	-0.1	-0.2
Illnesses of father: None of the above (group 1)	0.0	0.0	0.1	-0.3	-0.1
Ever depressed for a whole week	0.0	0.0	0.1	0.3	-0.0
Myopia	0.0	0.0	0.0	0.2	0.2
Supplements: Calcium	0.0	0.0	0.0	-0.1	0.2

Hub : Genes

LOC441454

Models

Trait associations