[Hub]/) : Traits : Arm predicted mass (left) :

chr10:69,348,758-70,981,217

Best TWAS P=1.44e-13 · Best GWAS P=7.66e-14 conditioned to 2.93e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum DNA2 0.32 0.18 lasso 9 0.20 1.9e-10 -5.3 5.4 6.2e-08 0.34 1.00 0.00 FALSE
2 GTEx Adrenal Gland DNA2 0.16 0.12 lasso 6 0.10 2.2e-04 -4.7 5.1 2.9e-07 0.31 0.48 0.08 FALSE
3 GTEx Artery Aorta DNA2 0.22 0.17 lasso 6 0.16 5.1e-09 -4.7 5.3 1.5e-07 0.32 1.00 0.00 FALSE
4 GTEx Artery Coronary DNA2 0.12 0.12 lasso 5 0.12 5.3e-05 -5.3 5.7 1.5e-08 0.35 0.30 0.23 FALSE
5 GTEx Brain Cerebellum SLC25A16 0.22 0.15 lasso 9 0.19 2.2e-06 -4.8 -5.2 1.6e-07 -0.33 0.32 0.06 FALSE
6 GTEx Brain Hypothalamus SLC25A16 0.20 0.19 lasso 5 0.14 3.6e-04 -5.3 -5.3 9.1e-08 -0.32 0.15 0.05 FALSE
7 GTEx Cells EBV-transformed lymphocytes DNA2 0.32 0.14 lasso 2 0.10 2.9e-04 -5.3 5.3 1.3e-07 0.33 0.44 0.08 FALSE
8 GTEx Cells Transformed fibroblasts SLC25A16 0.10 0.02 enet 25 0.01 2.5e-02 -4.4 -6.3 3.2e-10 -0.54 0.69 0.20 FALSE
9 GTEx Esophagus Muscularis DNA2 0.35 0.24 enet 10 0.33 9.3e-21 -5.3 5.1 2.9e-07 0.32 1.00 0.00 FALSE
10 GTEx Heart Atrial Appendage PBLD 0.08 0.02 lasso 2 0.02 6.1e-02 -6.8 -6.7 1.5e-11 -0.41 0.11 0.14 FALSE
11 GTEx Lung DNA2 0.22 0.17 enet 12 0.24 3.9e-18 -5.3 5.4 5.6e-08 0.35 1.00 0.00 FALSE
12 GTEx Muscle Skeletal DNA2 0.18 0.16 lasso 4 0.19 1.7e-18 -4.7 5.2 2.6e-07 0.30 1.00 0.00 FALSE
13 GTEx Ovary DNA2 0.15 0.12 lasso 3 0.06 1.7e-02 -5.0 5.2 1.9e-07 0.34 0.12 0.06 FALSE
14 GTEx Pancreas DNA2 0.12 0.06 enet 9 0.08 4.1e-04 -4.5 5.8 6.5e-09 0.40 0.34 0.36 FALSE
15 GTEx Skin Not Sun Exposed Suprapubic DNA2 0.29 0.16 lasso 14 0.22 2.4e-12 -4.7 5.4 6.5e-08 0.32 1.00 0.00 FALSE
16 GTEx Stomach DNA2 0.31 0.13 lasso 11 0.19 2.3e-09 -4.7 5.2 2.5e-07 0.32 0.94 0.06 FALSE
17 NTR Blood SLC25A16 0.03 0.02 enet 16 0.03 1.7e-09 -5.3 -5.6 1.8e-08 -0.41 0.70 0.30 FALSE
18 ROSMAP Brain Pre-frontal Cortex SLC25A16 0.17 0.11 lasso 6 0.15 2.9e-19 -4.5 -5.8 5.1e-09 -0.33 0.92 0.08 FALSE
19 YFS Blood SLC25A16 0.09 0.13 lasso 3 0.13 6.8e-39 -5.3 -5.7 1.1e-08 -0.35 0.89 0.11 FALSE
20 The Cancer Genome Atlas Bladder Urothelial Carcinoma PBLD 0.06 0.07 lasso 2 0.04 2.3e-04 -5.3 -5.3 1.0e-07 -0.32 0.02 0.96 FALSE
21 The Cancer Genome Atlas Breast Invasive Carcinoma SLC25A16 0.01 0.02 lasso 2 0.01 5.5e-04 -5.3 -5.3 1.3e-07 -0.33 0.34 0.07 FALSE
22 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma DNA2 0.08 0.09 lasso 1 0.06 7.3e-04 -6.8 6.8 1.0e-11 0.39 0.00 0.98 FALSE
23 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma DNA2 0.05 0.00 blup 43 0.00 3.0e-01 -5.3 6.0 2.4e-09 0.39 0.01 0.82 FALSE
24 The Cancer Genome Atlas Brain Lower Grade Glioma SLC25A16 0.05 0.01 blup 42 0.02 2.9e-03 -5.3 -5.9 3.1e-09 -0.51 0.11 0.72 FALSE
25 The Cancer Genome Atlas Lung Squamous Cell Carcinoma SLC25A16 0.02 0.02 enet 8 0.02 7.7e-04 -6.8 -6.4 1.2e-10 -0.38 0.07 0.22 FALSE
26 The Cancer Genome Atlas Soft Tissue Sarcoma SLC25A16 0.07 0.03 blup 42 0.02 1.7e-02 -6.8 -7.4 1.4e-13 -0.53 0.09 0.35 TRUE
27 The Cancer Genome Atlas Testicular Germ Cell Tumors DNA2 0.14 0.07 blup 43 0.08 8.6e-04 -5.4 -5.8 7.6e-09 -0.39 0.07 0.48 FALSE
28 The Cancer Genome Atlas Thyroid Carcinoma SLC25A16 0.05 0.05 lasso 3 0.04 3.8e-05 -5.3 -5.5 4.7e-08 -0.36 0.27 0.17 FALSE