Best TWAS P=3.06e-08 · Best GWAS P=2.35e-07 conditioned to 0.0213
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | POLR2L | 0.03 | 0.02 | bslmm | 413 | 0.01 | 0.00496 | -2.6 | -5.5 | 5.1e-08 | 0.6 | 0.17 | 0.14 | FALSE |
| 2 | The Cancer Genome Atlas | Lung Adenocarcinoma | TSPAN4 | 0.09 | 0.04 | enet | 9 | 0.03 | 0.00019 | 3.6 | 5.5 | 3.1e-08 | -0.6 | 0.16 | 0.53 | TRUE |