Best TWAS P=2.5e-09 · Best GWAS P=5.13e-10 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | PTPRJ | 0.05 | 0.05 | lasso | 2 | 0.04 | 0.00039 | 6.2 | 6.0 | 2.5e-09 | 0.99 | 0.01 | 0.97 | TRUE |
2 | ROSMAP | Brain Pre-frontal Cortex | CELF1 | 0.03 | 0.01 | bslmm | 289 | 0.01 | 0.02940 | 4.7 | 5.6 | 1.7e-08 | 0.45 | 0.05 | 0.72 | FALSE |