[Hub]/) : Traits : Arm predicted mass (left) :

chr14:24,098,631-25,546,115

Best TWAS P=1.84e-12 · Best GWAS P=9.1e-12 conditioned to 3.07e-57

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Heart Atrial Appendage ADCY4 0.28 0.14 lasso 4 0.10 2.1e-05 6.6 5.6 2.3e-08 0.88 0.01 0.97 TRUE
2 GTEx Spleen NFATC4 0.45 0.00 enet 24 0.00 2.5e-01 4.1 -5.8 6.4e-09 -0.28 0.06 0.06 TRUE
3 GTEx Thyroid ADCY4 0.13 0.13 lasso 6 0.09 1.0e-07 3.8 5.2 2.1e-07 0.78 0.08 0.92 FALSE
4 METSIM Adipose ADCY4 0.07 0.03 lasso 5 0.03 2.2e-05 6.8 7.0 1.8e-12 0.93 0.01 0.99 TRUE
5 The Cancer Genome Atlas Bladder Urothelial Carcinoma ADCY4 0.03 0.01 blup 75 0.03 1.1e-03 4.3 5.3 9.9e-08 0.78 0.03 0.86 FALSE
6 The Cancer Genome Atlas Colon Adenocarcinoma ADCY4 0.07 0.02 lasso 4 0.03 4.7e-03 4.8 5.4 6.3e-08 0.79 0.03 0.77 TRUE
7 The Cancer Genome Atlas Brain Lower Grade Glioma ADCY4 0.06 0.06 lasso 6 0.09 3.0e-10 5.7 6.7 1.6e-11 0.87 0.01 0.99 FALSE
8 The Cancer Genome Atlas Lung Adenocarcinoma ADCY4 0.07 0.09 lasso 3 0.08 4.4e-10 4.8 5.9 4.9e-09 0.81 0.85 0.15 FALSE
9 The Cancer Genome Atlas Stomach Adenocarcinoma LTB4R2 0.04 0.04 lasso 1 0.02 2.5e-02 5.3 -5.3 1.4e-07 -0.55 0.04 0.50 FALSE