[Hub]/) : Traits : Arm predicted mass (left) :

chr14:34,480,400-36,571,554

Best TWAS P=1.35e-11 · Best GWAS P=1.87e-09 conditioned to 0.29

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PPP2R3C 0.21 0.12 lasso 10 0.14 2.6e-11 -6.0 5.5 3.2e-08 -0.95 0.00 1.00 FALSE
2 GTEx Artery Tibial RP11-85K15.2 0.06 0.01 lasso 6 0.02 2.1e-02 -5.6 -5.8 6.2e-09 0.67 0.04 0.77 FALSE
3 GTEx Cells Transformed fibroblasts PPP2R3C 0.31 0.10 lasso 10 0.18 4.0e-13 -6.0 5.7 1.3e-08 -0.87 0.00 1.00 FALSE
4 GTEx Cells Transformed fibroblasts CFL2 0.14 0.08 enet 39 0.11 9.9e-09 -2.0 -6.8 1.4e-11 0.30 0.59 0.04 TRUE
5 NTR Blood NFKBIA 0.26 0.09 lasso 10 0.12 3.4e-36 -4.1 -5.9 2.9e-09 0.42 0.96 0.03 FALSE
6 YFS Blood KIAA0391 0.29 0.36 lasso 7 0.38 5.8e-132 -6.0 -5.8 5.2e-09 0.99 0.00 1.00 FALSE
7 YFS Blood NFKBIA 0.24 0.11 enet 33 0.17 3.5e-53 -4.0 -6.1 8.8e-10 0.51 0.97 0.02 TRUE
8 YFS Blood PPP2R3C 0.53 0.46 bslmm 383 0.60 2.4e-254 3.9 -5.6 2.2e-08 0.63 0.98 0.02 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma KIAA0391 0.07 0.04 blup 110 0.04 1.9e-05 -3.7 5.5 4.3e-08 -0.83 0.03 0.96 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma PPP2R3C 0.08 0.04 blup 51 0.07 7.8e-09 -4.9 6.1 8.9e-10 -0.82 0.01 0.99 FALSE
11 The Cancer Genome Atlas Thyroid Carcinoma KIAA0391 0.12 0.11 enet 14 0.14 2.0e-13 -4.4 5.5 3.0e-08 -0.77 0.54 0.46 FALSE