[Hub]/) : Traits : Arm predicted mass (left) :

chr16:13,697,975-15,886,243

Best TWAS P=4.6e-12 · Best GWAS P=1.45e-08 conditioned to 0.0527

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous NTAN1 0.05 0.03 lasso 2 0.04 6.7e-04 -5.6 6.2 6.6e-10 -0.93 0.01 0.96 TRUE
2 GTEx Artery Tibial RRN3 0.11 0.06 lasso 2 0.07 2.0e-06 5.5 5.2 1.7e-07 -0.49 0.02 0.98 FALSE
3 GTEx Cells EBV-transformed lymphocytes RRN3 0.36 0.14 lasso 5 0.20 4.5e-07 5.5 5.7 1.6e-08 -0.60 0.02 0.98 FALSE
4 GTEx Cells EBV-transformed lymphocytes RP11-958N24.1 0.22 0.02 lasso 5 0.06 4.8e-03 -2.7 5.2 1.9e-07 -0.60 0.02 0.45 FALSE
5 GTEx Cells Transformed fibroblasts RRN3 0.10 0.12 enet 13 0.13 6.3e-10 5.5 6.2 6.5e-10 -0.59 0.02 0.98 FALSE
6 GTEx Colon Transverse RRN3 0.13 0.00 lasso 5 0.00 1.9e-01 5.3 -5.8 5.8e-09 0.30 0.02 0.44 FALSE
7 GTEx Esophagus Mucosa RRN3 0.13 0.13 lasso 4 0.13 3.2e-09 5.3 5.1 2.9e-07 -0.51 0.02 0.98 FALSE
8 GTEx Heart Atrial Appendage NOMO1 0.19 0.12 lasso 6 0.10 3.7e-05 5.3 5.3 1.2e-07 -0.48 0.03 0.89 FALSE
9 GTEx Heart Atrial Appendage NTAN1 0.10 0.09 lasso 1 0.07 3.7e-04 5.3 5.3 1.1e-07 -0.49 0.02 0.74 FALSE
10 GTEx Heart Left Ventricle RRN3 0.24 0.12 lasso 7 0.17 2.2e-09 5.3 -6.6 4.2e-11 0.39 0.03 0.97 FALSE
11 GTEx Heart Left Ventricle NTAN1 0.09 0.04 lasso 3 0.02 2.0e-02 5.5 5.4 5.3e-08 -0.48 0.02 0.80 FALSE
12 GTEx Muscle Skeletal RRN3 0.18 0.03 enet 17 0.11 5.7e-11 4.8 -6.0 2.3e-09 0.37 0.15 0.74 FALSE
13 GTEx Muscle Skeletal NTAN1 0.12 0.07 lasso 6 0.09 1.4e-09 5.3 6.1 1.4e-09 -0.46 0.02 0.98 FALSE
14 GTEx Nerve Tibial NTAN1 0.07 0.00 enet 14 0.00 1.7e-01 5.5 6.9 4.6e-12 -0.17 0.02 0.26 TRUE
15 GTEx Skin Sun Exposed Lower leg RRN3 0.10 0.12 lasso 1 0.11 4.5e-09 5.5 5.5 3.3e-08 -0.48 0.02 0.98 FALSE
16 GTEx Testis RRN3 0.10 0.10 lasso 2 0.07 3.9e-04 5.5 5.5 3.3e-08 -0.48 0.02 0.85 FALSE
17 GTEx Thyroid RP11-65J21.3 0.35 0.32 lasso 2 0.31 2.6e-24 -5.2 -5.2 1.9e-07 -0.03 0.03 0.97 TRUE
18 NTR Blood NTAN1 0.01 0.00 bslmm 110 0.00 4.2e-02 5.5 6.1 1.1e-09 -0.23 0.01 0.26 FALSE
19 NTR Blood PDXDC1 0.12 0.12 enet 26 0.15 1.3e-46 -5.6 6.8 1.4e-11 -0.84 0.01 0.99 FALSE
20 ROSMAP Brain Pre-frontal Cortex NTAN1 0.12 0.10 lasso 3 0.11 1.4e-13 5.3 5.4 8.0e-08 -0.48 0.03 0.97 FALSE