[Hub]/) : Traits : Arm predicted mass (left) :

chr16:81,485,946-82,901,701

Best TWAS P=7.32e-10 · Best GWAS P=1.33e-09 conditioned to 8.84e-10

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum MPHOSPH6 0.32 0.14 lasso 4 0.17 3.5e-09 4.9 5.1 2.7e-07 -0.02 0.01 0.98 FALSE
2 GTEx Artery Tibial MPHOSPH6 0.36 0.24 enet 9 0.27 1.9e-21 5.4 5.2 2.2e-07 -0.02 0.00 1.00 FALSE
3 GTEx Brain Cerebellar Hemisphere MPHOSPH6 0.49 0.30 enet 12 0.31 8.5e-09 5.4 5.3 1.4e-07 -0.02 0.01 0.99 FALSE
4 GTEx Colon Transverse MPHOSPH6 0.21 0.16 lasso 3 0.17 1.4e-08 5.4 5.3 1.1e-07 -0.02 0.00 0.99 FALSE
5 GTEx Esophagus Muscularis MPHOSPH6 0.36 0.23 lasso 7 0.20 1.7e-12 5.4 5.4 6.8e-08 -0.03 0.00 1.00 FALSE
6 GTEx Heart Left Ventricle MPHOSPH6 0.28 0.24 lasso 3 0.24 8.9e-13 5.4 5.4 7.0e-08 -0.02 0.00 1.00 FALSE
7 GTEx Lung MPHOSPH6 0.16 0.10 lasso 4 0.11 8.3e-09 5.4 5.2 1.7e-07 -0.03 0.01 0.99 FALSE
8 GTEx Nerve Tibial MPHOSPH6 0.40 0.22 lasso 7 0.28 1.0e-19 5.4 5.5 3.3e-08 -0.03 0.00 1.00 FALSE
9 GTEx Stomach MPHOSPH6 0.41 0.10 lasso 7 0.09 3.5e-05 4.6 6.2 7.3e-10 -0.01 0.01 0.98 TRUE
10 GTEx Testis MPHOSPH6 0.52 0.32 lasso 11 0.35 2.0e-16 5.4 5.2 1.7e-07 -0.03 0.00 1.00 FALSE
11 GTEx Thyroid MPHOSPH6 0.31 0.21 lasso 4 0.26 4.7e-20 4.9 5.2 1.8e-07 -0.02 0.01 0.98 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma MPHOSPH6 0.18 0.16 lasso 3 0.16 5.1e-15 5.4 5.3 1.1e-07 -0.03 0.00 1.00 FALSE