[Hub]/) : Traits : Arm predicted mass (left) :

chr16:71,070,698-72,569,466

Best TWAS P=1.88e-09 · Best GWAS P=5.3e-10 conditioned to 2.56e-06

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PHLPP2 0.04 0.01 bslmm 456 0.02 4.7e-04 -4.4 -5.7 9.9e-09 0.57 0.36 0.56 FALSE
2 GTEx Adrenal Gland AP1G1 0.22 0.06 enet 25 0.14 8.0e-06 -5.2 -5.3 1.4e-07 0.58 0.22 0.74 FALSE
3 METSIM Adipose PHLPP2 0.07 0.03 lasso 5 0.06 1.7e-09 4.5 5.7 1.5e-08 -0.46 0.88 0.12 FALSE
4 YFS Blood ATXN1L 0.02 0.02 blup 413 0.02 6.5e-07 3.6 5.5 2.8e-08 -0.45 0.93 0.06 FALSE
5 YFS Blood PHLPP2 0.04 0.03 bslmm 459 0.05 5.5e-16 -5.2 5.9 4.7e-09 -0.52 0.36 0.64 FALSE
6 The Cancer Genome Atlas Prostate Adenocarcinoma AP1G1 0.11 0.02 enet 27 0.04 1.2e-04 4.5 -6.0 1.9e-09 0.28 0.06 0.40 TRUE
7 The Cancer Genome Atlas Testicular Germ Cell Tumors PHLPP2 0.11 0.03 lasso 6 0.01 1.2e-01 4.4 5.6 2.3e-08 -0.43 0.03 0.44 FALSE
8 The Cancer Genome Atlas Thyroid Carcinoma MARVELD3 0.08 0.01 blup 44 0.06 7.1e-07 -5.3 5.4 7.5e-08 -0.49 0.03 0.95 FALSE
9 The Cancer Genome Atlas Thyroid Carcinoma PHLPP2 0.20 0.08 blup 67 0.14 1.4e-13 4.7 5.1 2.9e-07 -0.32 0.25 0.75 FALSE