Best TWAS P=1.88e-09 · Best GWAS P=5.3e-10 conditioned to 2.56e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | PHLPP2 | 0.04 | 0.01 | bslmm | 456 | 0.02 | 4.7e-04 | -4.4 | -5.7 | 9.9e-09 | 0.57 | 0.36 | 0.56 | FALSE |
| 2 | GTEx | Adrenal Gland | AP1G1 | 0.22 | 0.06 | enet | 25 | 0.14 | 8.0e-06 | -5.2 | -5.3 | 1.4e-07 | 0.58 | 0.22 | 0.74 | FALSE |
| 3 | METSIM | Adipose | PHLPP2 | 0.07 | 0.03 | lasso | 5 | 0.06 | 1.7e-09 | 4.5 | 5.7 | 1.5e-08 | -0.46 | 0.88 | 0.12 | FALSE |
| 4 | YFS | Blood | ATXN1L | 0.02 | 0.02 | blup | 413 | 0.02 | 6.5e-07 | 3.6 | 5.5 | 2.8e-08 | -0.45 | 0.93 | 0.06 | FALSE |
| 5 | YFS | Blood | PHLPP2 | 0.04 | 0.03 | bslmm | 459 | 0.05 | 5.5e-16 | -5.2 | 5.9 | 4.7e-09 | -0.52 | 0.36 | 0.64 | FALSE |
| 6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | AP1G1 | 0.11 | 0.02 | enet | 27 | 0.04 | 1.2e-04 | 4.5 | -6.0 | 1.9e-09 | 0.28 | 0.06 | 0.40 | TRUE |
| 7 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | PHLPP2 | 0.11 | 0.03 | lasso | 6 | 0.01 | 1.2e-01 | 4.4 | 5.6 | 2.3e-08 | -0.43 | 0.03 | 0.44 | FALSE |
| 8 | The Cancer Genome Atlas | Thyroid Carcinoma | MARVELD3 | 0.08 | 0.01 | blup | 44 | 0.06 | 7.1e-07 | -5.3 | 5.4 | 7.5e-08 | -0.49 | 0.03 | 0.95 | FALSE |
| 9 | The Cancer Genome Atlas | Thyroid Carcinoma | PHLPP2 | 0.20 | 0.08 | blup | 67 | 0.14 | 1.4e-13 | 4.7 | 5.1 | 2.9e-07 | -0.32 | 0.25 | 0.75 | FALSE |