Best TWAS P=2.33e-10 · Best GWAS P=7.09e-43 conditioned to 5.26e-25
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | LOC730102 | 0.18 | 0.12 | lasso | 9 | 0.12 | 1.4e-14 | 5.061 | -5.7 | 1.4e-08 | -0.31 | 1.00 | 0.00 | FALSE |
| 2 | GTEx | Lung | RASAL2-AS1 | 0.14 | 0.01 | lasso | 7 | 0.05 | 1.1e-04 | -0.075 | 6.3 | 2.3e-10 | 0.49 | 0.52 | 0.09 | TRUE |
| 3 | GTEx | Muscle Skeletal | SEC16B | 0.18 | 0.04 | lasso | 6 | 0.05 | 2.3e-05 | 5.061 | 5.7 | 1.6e-08 | 0.32 | 0.47 | 0.02 | FALSE |
| 4 | GTEx | Muscle Skeletal | RP4-798P15.3 | 0.18 | 0.02 | lasso | 6 | 0.04 | 1.7e-04 | 5.061 | 5.6 | 2.0e-08 | 0.32 | 0.28 | 0.03 | FALSE |
| 5 | GTEx | Skin Sun Exposed Lower leg | RASAL2-AS1 | 0.06 | 0.00 | enet | 23 | 0.02 | 1.8e-02 | -5.446 | 6.0 | 2.2e-09 | 0.24 | 0.13 | 0.04 | TRUE |
| 6 | GTEx | Skin Sun Exposed Lower leg | RP11-568K15.1 | 0.11 | 0.05 | enet | 20 | 0.04 | 1.3e-04 | 5.061 | -5.9 | 3.2e-09 | -0.38 | 0.57 | 0.11 | TRUE |