Best TWAS P=2.36e-10 · Best GWAS P=6.7e-08 conditioned to 0.177
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Breast Mammary Tissue (Male) | CST7 | 0.15 | 0.0 | lasso | 4 | 0.03 | 7.0e-02 | -4.1 | -5.2 | 2.2e-07 | 0.62 | 0.06 | 0.06 | FALSE |
2 | ROSMAP | Brain Pre-frontal Cortex | ENTPD6 | 0.32 | 0.1 | bslmm | 432 | 0.12 | 1.8e-15 | 4.5 | 6.3 | 2.4e-10 | -0.70 | 0.17 | 0.82 | TRUE |