[Hub]/) : Traits : Arm predicted mass (left) : ← →

chr20:19,649,716-21,919,054

Best TWAS P=6.28e-16 · Best GWAS P=1.24e-17 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex INSM1 0.07 0.00 bslmm 522 0.02 2.2e-03 3.70 5.3 8.9e-08 -0.01 0.09 0.09 TRUE
2 CommonMind Brain Pre-frontal Cortex PLK1S1 0.08 0.01 lasso 3 0.04 1.1e-05 6.55 6.3 3.4e-10 0.82 0.02 0.98 FALSE
3 GTEx Artery Tibial PLK1S1 0.07 0.08 enet 10 0.08 4.0e-07 8.42 8.1 6.3e-16 0.97 0.01 0.99 TRUE
4 GTEx Esophagus Mucosa PLK1S1 0.11 0.11 lasso 5 0.09 7.8e-07 6.44 6.4 1.5e-10 0.83 0.12 0.88 FALSE
5 GTEx Heart Atrial Appendage PLK1S1 0.15 -0.01 lasso 4 0.00 6.1e-01 0.93 5.6 2.1e-08 0.56 0.05 0.41 FALSE
6 GTEx Skin Not Sun Exposed Suprapubic PLK1S1 0.21 0.09 lasso 6 0.12 5.3e-07 8.09 6.9 5.0e-12 0.93 0.07 0.93 FALSE
7 GTEx Skin Sun Exposed Lower leg PLK1S1 0.15 0.13 enet 10 0.15 3.9e-12 6.42 6.0 1.9e-09 0.83 0.90 0.10 FALSE
8 GTEx Testis PLK1S1 0.64 0.34 enet 33 0.39 1.0e-18 6.42 6.8 1.2e-11 0.79 0.67 0.33 FALSE
9 GTEx Whole Blood PLK1S1 0.08 0.04 enet 9 0.02 4.0e-03 6.42 7.2 7.1e-13 0.89 0.06 0.93 FALSE
10 The Cancer Genome Atlas Breast Invasive Carcinoma PLK1S1 0.05 0.07 enet 9 0.07 5.5e-15 6.19 6.9 6.0e-12 0.88 0.15 0.85 FALSE
11 The Cancer Genome Atlas Lung Adenocarcinoma PLK1S1 0.04 0.03 blup 64 0.04 4.0e-05 6.42 7.5 9.4e-14 0.88 0.12 0.88 FALSE
12 The Cancer Genome Atlas Pancreatic Adenocarcinoma PLK1S1 0.09 0.02 blup 64 0.05 3.1e-03 6.55 7.5 4.2e-14 0.78 0.03 0.53 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma PLK1S1 0.19 0.12 enet 14 0.13 4.3e-13 6.46 6.5 7.1e-11 0.80 0.90 0.10 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma PLK1S1 0.06 0.04 lasso 3 0.04 1.5e-04 6.46 6.6 3.7e-11 0.85 0.15 0.60 FALSE