[Hub]/) : Traits : Arm predicted mass (left) : ← →

chr1:10,391,536-12,013,869

Best TWAS P=1.85e-16 · Best GWAS P=4.06e-15 conditioned to 0.0117

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	EXOSC10	0.06	0.08	lasso	2	0.07	6.8e-09	7.8	7.9	2.6e-15	0.99	0.01	0.99	FALSE
2	CommonMind	Brain Pre-frontal Cortex	MTOR	0.13	0.15	lasso	4	0.15	5.6e-18	7.6	7.4	1.5e-13	0.88	0.06	0.94	FALSE
3	GTEx	Adipose Subcutaneous	MASP2	0.10	0.06	lasso	2	0.03	8.8e-04	6.2	6.2	7.8e-10	0.69	0.45	0.36	FALSE
4	GTEx	Adipose Subcutaneous	EXOSC10	0.17	0.00	lasso	3	0.00	1.8e-01	7.7	6.9	4.6e-12	0.94	0.02	0.48	FALSE
5	GTEx	Adipose Visceral Omentum	RP4-635E18.7	0.19	0.08	lasso	6	0.05	9.0e-04	7.9	7.2	4.5e-13	0.96	0.02	0.96	FALSE
6	GTEx	Artery Tibial	EXOSC10	0.09	0.02	lasso	5	0.01	6.6e-02	5.9	-5.2	2.4e-07	0.10	0.07	0.47	TRUE
7	GTEx	Brain Cerebellar Hemisphere	EXOSC10	0.23	0.10	lasso	3	0.12	6.4e-04	7.3	7.7	1.6e-14	0.90	0.04	0.80	FALSE
8	GTEx	Brain Cerebellum	EXOSC10	0.33	0.16	lasso	6	0.18	3.8e-06	7.7	7.8	6.4e-15	0.94	0.03	0.96	FALSE
9	GTEx	Brain Cerebellum	RP4-635E18.7	0.17	0.17	lasso	5	0.09	1.3e-03	7.7	7.8	8.8e-15	0.96	0.03	0.92	FALSE
10	GTEx	Brain Cortex	RP4-635E18.7	0.17	0.05	lasso	4	0.07	6.4e-03	7.6	7.6	2.4e-14	0.91	0.05	0.75	FALSE
11	GTEx	Lung	EXOSC10	0.11	0.07	lasso	4	0.05	1.2e-04	7.7	7.5	4.7e-14	0.97	0.02	0.97	FALSE
12	GTEx	Nerve Tibial	MASP2	0.14	0.07	lasso	5	0.09	1.2e-06	6.2	5.8	5.5e-09	0.68	0.42	0.46	FALSE
13	GTEx	Thyroid	RP4-635E18.7	0.07	0.02	lasso	2	0.01	5.5e-02	7.7	7.7	1.7e-14	0.93	0.02	0.87	FALSE
14	GTEx	Whole Blood	MTOR	0.16	0.06	enet	18	0.07	5.1e-07	7.2	5.7	1.1e-08	0.66	0.43	0.56	FALSE
15	METSIM	Adipose	EXOSC10	0.05	0.06	lasso	1	0.05	3.5e-08	6.4	6.4	1.2e-10	0.85	0.02	0.98	FALSE
16	METSIM	Adipose	MTOR	0.04	0.02	bslmm	434	0.02	1.5e-04	7.6	8.0	1.4e-15	0.89	0.04	0.96	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	EXOSC10	0.06	0.06	lasso	2	0.06	4.9e-08	7.8	7.8	7.0e-15	1.00	0.02	0.98	FALSE
18	ROSMAP	Brain Pre-frontal Cortex	MTOR	0.07	0.05	bslmm	423	0.04	2.0e-06	7.6	8.2	1.8e-16	0.87	0.08	0.92	TRUE
19	ROSMAP	Brain Pre-frontal Cortex	RP4-635E18.7	0.23	0.09	enet	24	0.24	3.8e-30	5.5	5.6	1.9e-08	0.71	0.02	0.98	FALSE
20	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MTOR	0.02	0.02	blup	54	0.02	5.4e-03	7.6	7.7	1.0e-14	0.91	0.04	0.78	FALSE
21	The Cancer Genome Atlas	Brain Lower Grade Glioma	MTOR	0.03	0.01	blup	54	0.02	5.9e-03	7.6	7.5	9.5e-14	0.88	0.03	0.72	FALSE
22	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	MASP2	0.05	0.03	blup	30	0.04	6.0e-03	2.8	-6.9	4.2e-12	-0.84	0.02	0.58	FALSE