Best TWAS P=1.74e-08 · Best GWAS P=5.89e-08 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | RP11-738E22.3 | 0.07 | 0.04 | lasso | 6 | 0.05 | 7.7e-08 | -5.4 | 5.6 | 1.7e-08 | -0.98 | 0.00 | 1.00 | TRUE |
2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | REST | 0.04 | 0.01 | lasso | 5 | 0.02 | 7.8e-04 | -5.4 | -5.5 | 4.1e-08 | 0.86 | 0.01 | 0.96 | FALSE |