Best TWAS P=5.18e-08 · Best GWAS P=1.53e-06 conditioned to 0.218
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Visceral Omentum | RFWD3 | 0.14 | 0.03 | enet | 15 | 0.04 | 3.0e-03 | 4.0 | 5.5 | 5.2e-08 | -0.73 | 0.05 | 0.83 | TRUE |
2 | GTEx | Breast Mammary Tissue (Male) | GLG1 | 0.20 | -0.01 | lasso | 5 | 0.02 | 8.9e-02 | -4.8 | 5.1 | 2.9e-07 | -0.91 | 0.02 | 0.38 | FALSE |
3 | GTEx | Esophagus Muscularis | RFWD3 | 0.18 | 0.07 | lasso | 5 | 0.10 | 1.4e-06 | -4.8 | 5.1 | 2.8e-07 | -0.77 | 0.02 | 0.94 | FALSE |
4 | GTEx | Skin Not Sun Exposed Suprapubic | RFWD3 | 0.20 | 0.14 | lasso | 5 | 0.15 | 9.2e-09 | -4.8 | 5.2 | 2.5e-07 | -0.83 | 0.01 | 0.97 | FALSE |
5 | GTEx | Stomach | RFWD3 | 0.20 | 0.08 | enet | 20 | 0.13 | 1.2e-06 | 4.1 | 5.3 | 1.4e-07 | -0.71 | 0.03 | 0.93 | FALSE |